Gabriel G Perrone
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Explore the profile of Gabriel G Perrone including associated specialties, affiliations and a list of published articles.
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22
Citations
657
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Recent Articles
1.
Dawes I, Perrone G
FEMS Yeast Res
. 2019 Dec;
20(1).
PMID: 31816015
There has long been speculation about the role of various stresses in ageing. Some stresses have beneficial effects on ageing-dependent on duration and severity of the stress, others have negative...
2.
El-Khoury M, Ligot R, Mahoney S, Stack C, Perrone G, Morton C
BMC Res Notes
. 2017 Aug;
10(1):364.
PMID: 28764751
Objective: Recent studies into the antifungal activity of NK-cells against the Aspergillus fumigatus have presented differing accounts on their mode of antifungal activity. One of these mechanisms proposed that NK-cells...
3.
Johnson A, Zaman M, Veljanoski F, Phrakaysone A, Li S, ODoherty P, et al.
Metallomics
. 2017 Feb;
9(3):301-308.
PMID: 28194465
Metal ions, biologically essential or toxic, are present in the surrounding environment of living organisms. Understanding their uptake, homeostasis or detoxification is critical in cell biology and human health. In...
4.
Serhan G, Stack C, Perrone G, Morton C
Ann Clin Microbiol Antimicrob
. 2014 Jun;
13:18.
PMID: 24884795
Background: There is a pressing need to identify novel antifungal drug targets to aid in the therapy of life-threatening mycoses and overcome increasing drug resistance. Identifying specific mechanisms of action...
5.
Jarolim S, Ayer A, Pillay B, Gee A, Phrakaysone A, Perrone G, et al.
G3 (Bethesda)
. 2013 Oct;
3(12):2321-33.
PMID: 24142923
The heat-shock response in cells, involving increased transcription of a specific set of genes in response to a sudden increase in temperature, is a highly conserved biological response occurring in...
6.
Tun N, ODoherty P, Perrone G, Bailey T, Kersaitis C, Wu M
Metallomics
. 2013 Jul;
5(8):1068-75.
PMID: 23832094
Formation of non-native disulfide bonds within or between proteins can lead to protein misfolding and disruption to cellular metabolism. Such a process is defined as disulfide stress. A marked effect...
7.
Ayer A, Sanwald J, Pillay B, Meyer A, Perrone G, Dawes I
PLoS One
. 2013 Jun;
8(6):e65240.
PMID: 23762325
Responses to many growth and stress conditions are assumed to act via changes to the cellular redox status. However, direct measurement of pH-adjusted redox state during growth and stress has...
8.
Breitenbach M, Ralser M, Perrone G, Iglseder B, Rinnerthaler M, Dawes I
Front Biosci (Landmark Ed)
. 2013 Jun;
18(3):1174-93.
PMID: 23747875
In this chapter we are treating yeast cells as a model for oxidative stress response and the consequences of oxidative stress which are one cause for a number of human...
9.
Ayer A, Fellermeier S, Fife C, Li S, Smits G, Meyer A, et al.
PLoS One
. 2012 Sep;
7(9):e44278.
PMID: 22970195
Maintenance of an optimal redox environment is critical for appropriate functioning of cellular processes and cell survival. Despite the importance of maintaining redox homeostasis, it is not clear how the...
10.
Park D, Chiu J, Perrone G, Dilda P, Hogg P
Cancer Cell Int
. 2012 Mar;
12(1):11.
PMID: 22448968
Background: GSAO (4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid) and PENAO (4-(N-(S-penicillaminylacetyl)amino) phenylarsonous acid) are tumour metabolism inhibitors that target adenine nucleotide translocase (ANT) of the inner-mitochondrial membrane. Both compounds are currently being trialled...