Hongchang Qu
Overview
Explore the profile of Hongchang Qu including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
851
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0
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Recent Articles
1.
Ying Z, van Eenige R, Ge X, van Marwijk C, Lambooij J, Guigas B, et al.
EBioMedicine
. 2023 Jun;
93:104684.
PMID: 37379656
Background: Combined glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP1R) agonism is superior to single GLP1R agonism with respect to glycemic control and weight loss in obese patients...
2.
Urva S, OFarrell L, Du Y, Loh M, Hemmingway A, Qu H, et al.
Diabetes Obes Metab
. 2023 Jun;
25(9):2784-2788.
PMID: 37311727
No abstract available.
3.
Hu H, Ransdell A, Qu H, Durbin J, Valenzuela F, Hernandez-Buquer S, et al.
ACS Chem Biol
. 2023 May;
18(5):1158-1167.
PMID: 37145869
Peptides represent an increasingly important class of pharmaceutical products. During the last decade or so, acylation with fatty acids has demonstrated considerable success in prolonging the circulating half-life of therapeutic...
4.
van Eenige R, Ying Z, Tramper N, Wiebing V, Siraj Z, de Boer J, et al.
Atherosclerosis
. 2023 Apr;
372:19-31.
PMID: 37015151
Background And Aims: Combined agonism of the glucose-dependent insulinotropic polypeptide receptor (GIPR) and the glucagon-like peptide-1 receptor (GLP1R) is superior to single GLP1R agonism in terms of glycemic control and...
5.
Tran H, Aihara E, Mohammed F, Qu H, Riley A, Su Y, et al.
Mol Pharm
. 2023 Jan;
20(2):929-941.
PMID: 36592951
Sodium caprate (C10) has been widely evaluated as an intestinal permeation enhancer for the oral delivery of macromolecules. However, the effect of C10 on the intestinal absorption of peptides with...
6.
Coskun T, Urva S, Roell W, Qu H, Loghin C, Moyers J, et al.
Cell Metab
. 2022 Aug;
34(9):1234-1247.e9.
PMID: 35985340
With an increasing prevalence of obesity, there is a need for new therapies to improve body weight management and metabolic health. Multireceptor agonists in development may provide approaches to fulfill...
7.
Nilsson P, Ekdahl K, Magnusson P, Qu H, Iwata H, Ricklin D, et al.
Biomaterials
. 2012 Nov;
34(4):985-94.
PMID: 23137394
Activation of the thrombotic and complement systems is the main recognition and effector mechanisms in the multiple adverse biological responses triggered when biomaterials or therapeutic cells come into blood contact....
8.
Qu H, Ricklin D, Bai H, Chen H, Reis E, Maciejewski M, et al.
Immunobiology
. 2012 Jul;
218(4):496-505.
PMID: 22795972
Therapeutic modulation of the complement system has become increasingly important in line with the growing recognition of the role of complement in numerous diseases. Compstatin, a peptidic inhibitor that acts...
9.
Langer H, Choi E, Zhou H, Schleicher R, Chung K, Tang Z, et al.
Circ Res
. 2012 Mar;
110(9):1202-10.
PMID: 22456181
Rationale: Multiple sclerosis (MS) and its mouse model, experimental autoimmune encephalomyelitis (EAE), are inflammatory disorders of the central nervous system (CNS). The function of platelets in inflammatory and autoimmune pathologies...
10.
Liu Z, Mehta S, Lee K, Grossman B, Qu H, Gu X, et al.
J Org Chem
. 2012 Jan;
77(3):1289-300.
PMID: 22283513
Multifunctionalized amino acids, especially amino acids with unsaturation, are important, demanding building blocks in peptide chemistry. Here we present a summary of our most recent study using the thio-Claisen rearrangement...