Daniel Ricklin
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Explore the profile of Daniel Ricklin including associated specialties, affiliations and a list of published articles.
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128
Citations
7485
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Recent Articles
1.
Sommer-Pluss C, Leiggener C, Nikci E, Mancuso R, Rabbani S, Lamers C, et al.
Biomolecules
. 2025 Feb;
15(2).
PMID: 40001541
The family of the β-integrin receptors is critically involved in host defense and homeostasis, by mediating immune cell adhesion, migration, and phagocytosis. Due to their key roles in immune surveillance...
2.
van Beek A, Jeanguenat H, Haberli C, Pouw R, Lamers C, Pal G, et al.
Front Immunol
. 2024 Nov;
15:1474358.
PMID: 39600706
Background: Schistosomes are highly efficient evaders of human immunity, as evident by their ability to survive in human blood for years. How they protect themselves against the constant attack by...
3.
Ricklin D
Eur J Immunol
. 2024 Sep;
54(12):e2350816.
PMID: 39263829
Therapeutic interventions in the complement system, a key immune-inflammatory mediator and contributor to a broad range of clinical conditions, have long been considered important yet challenging or even unfeasible to...
4.
Kinzi J, Hussner J, Seibert I, Vythilingam M, Vonwyl C, Gherardi C, et al.
Drug Metab Dispos
. 2024 Jul;
52(9):957-965.
PMID: 39038952
The organic anion transporting polypeptide (OATP) 2B1 is considered an emerging drug transporter that is found expressed in pharmacokinetically relevant organs such as the liver, small intestine, and kidney. Despite...
5.
Rysz M, Schafer A, Paloumpis N, Kinzi J, Brecht K, Seibert I, et al.
J Pharmacol Exp Ther
. 2024 Mar;
389(1):87-95.
PMID: 38448247
The organic anion transporting polypeptide (OATP)2B1 [(gene: solute carrier organic anion transporter family member 2B1 ()] is an uptake transporter that facilitates cellular accumulation of its substrates. Comparison of knockin...
6.
Conti G, Barenwaldt A, Rabbani S, Muhlethaler T, Sarcevic M, Jiang X, et al.
Angew Chem Int Ed Engl
. 2023 Nov;
62(52):e202314280.
PMID: 37947772
Carbohydrate-binding proteins are generally characterized by poor affinities for their natural glycan ligands, predominantly due to the shallow and solvent-exposed binding sites. To overcome this drawback, nature has exploited multivalency...
7.
Golomingi M, Kohler J, Lamers C, Pouw R, Ricklin D, Dobo J, et al.
Front Immunol
. 2023 Sep;
14:1226832.
PMID: 37771595
Background: Haemostasis is a crucial process by which the body stops bleeding. It is achieved by the formation of a platelet plug, which is strengthened by formation of a fibrin...
8.
Rysz M, Kinzi J, Schafer A, In-Albon K, Zurcher S, Schmidlin S, et al.
J Pharm Biomed Anal
. 2023 Sep;
236:115716.
PMID: 37722165
Erlotinib is an epidermal growth factor receptor tyrosine kinase inhibitor used in the treatment of cancer. Atorvastatin is a statin commonly applied to treat hypercholesterolemia. In humans, both compounds are...
9.
Bechtler C, Barneoud-Rousset O, Pang L, Martin K, Konig K, Hanggi P, et al.
Chem Biol Drug Des
. 2023 May;
102(3):580-586.
PMID: 37186370
IgA nephropathy (IgAN) is the most common glomerular autoimmune disease and has severe long-term consequences for patients, with 40% of the patients eventually progressing to end-stage renal disease. Despite the...
10.
Lamers C, Ricklin D, Lambris J
Am J Hematol
. 2023 Feb;
98 Suppl 4:S82-S89.
PMID: 36755352
Within a short few years, the number of complement inhibitors that are either approved for therapeutic application or evaluated in late-stage clinical trials has expanded remarkably. The sudden emergence of...