Himjyot Jaiswal
Overview
Explore the profile of Himjyot Jaiswal including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
241
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0
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Recent Articles
1.
Meseguer-Ripolles J, Lucendo-Villarin B, Tucker C, Ferreira-Gonzalez S, Homer N, Wang Y, et al.
iScience
. 2021 Jun;
24(6):102552.
PMID: 34151225
Liver disease is a major cause of premature death. Oxidative stress in the liver represents a key disease driver. Compounds, such as dimethyl fumarate (DMF), can activate the antioxidant response...
2.
Ruiz M, Palmgren H, Henricsson M, Devkota R, Jaiswal H, Maresca M, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2021 Jan;
1866(4):158884.
PMID: 33444759
How cells maintain vital membrane lipid homeostasis while obtaining most of their constituent fatty acids from a varied diet remains largely unknown. Here, we used transcriptomics, lipidomics, growth and respiration...
3.
Lundin A, Porritt M, Jaiswal H, Seeliger F, Johansson C, Bidar A, et al.
Nat Commun
. 2020 Sep;
11(1):4903.
PMID: 32994412
The CRISPR-Cas9 system has increased the speed and precision of genetic editing in cells and animals. However, model generation for drug development is still expensive and time-consuming, demanding more target...
4.
Ross-Thriepland D, Bornot A, Butler L, Desai A, Jaiswal H, Peel S, et al.
SLAS Discov
. 2020 May;
25(6):605-617.
PMID: 32441189
Modified messenger RNAs (mRNAs) hold great potential as therapeutics by using the body's own processes for protein production. However, a key challenge is efficient delivery of therapeutic mRNA to the...
5.
Gupta S, Wesolowska-Andersen A, Ringgaard A, Jaiswal H, Song L, Hastoy B, et al.
Stem Cell Res
. 2018 May;
29:220-231.
PMID: 29734117
Recent studies have reported significant advances in the differentiation of human pluripotent stem cells to clinically relevant cell types such as the insulin producing beta-like cells and motor neurons. However,...
6.
Jaiswal H, Benada J, Mullers E, Akopyan K, Burdova K, Koolmeister T, et al.
EMBO J
. 2017 Jun;
36(14):2161-2176.
PMID: 28607002
After DNA damage, the cell cycle is arrested to avoid propagation of mutations. Arrest in G2 phase is initiated by ATM-/ATR-dependent signaling that inhibits mitosis-promoting kinases such as Plk1. At...
7.
Jaiswal H, Lindqvist A
Front Genet
. 2015 Mar;
6:63.
PMID: 25774166
The DNA damage response (DDR) has two main goals, to repair the damaged DNA and to communicate the presence of damaged DNA. This communication allows the adaptation of cellular behavior...
8.
Mullers E, Silva Cascales H, Jaiswal H, Saurin A, Lindqvist A
Cell Cycle
. 2014 Dec;
13(17):2733-43.
PMID: 25486360
Upon DNA damage, cell cycle progression is temporally blocked to avoid propagation of mutations. While transformed cells largely maintain the competence to recover from a cell cycle arrest, untransformed cells...
9.
Akopyan K, Silva Cascales H, Hukasova E, Saurin A, Mullers E, Jaiswal H, et al.
Mol Cell
. 2014 Mar;
53(5):843-53.
PMID: 24582498
During the cell cycle, DNA duplication in S phase must occur before a cell divides in mitosis. In the intervening G2 phase, mitotic inducers accumulate, which eventually leads to a...
10.
Jaiswal H, Conz C, Otto H, Wolfle T, Fitzke E, Mayer M, et al.
Mol Cell Biol
. 2011 Jan;
31(6):1160-73.
PMID: 21245388
Mammalian ribosome-associated complex (mRAC), consisting of the J-domain protein MPP11 and the atypical Hsp70 homolog (70-homolog) Hsp70L1, can partly complement the function of RAC, which is the homologous complex from...