Henning Tidow
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Explore the profile of Henning Tidow including associated specialties, affiliations and a list of published articles.
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55
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1356
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Recent Articles
1.
Faucon A, Renault J, Josts I, Couchot J, Renaud J, Hoegy F, et al.
Bioorg Med Chem
. 2024 Aug;
112:117842.
PMID: 39173538
The decline of antibiotics efficacy worldwide has recently reached a critical point urging for the development of new strategies to regain upper hand on multidrug resistant bacterial strains. In this...
2.
Pick J, Sander S, Etzold S, Rosche A, Tidow H, Guse A, et al.
Front Immunol
. 2024 Feb;
15:1294357.
PMID: 38318185
TRPM2 is a Ca permeable, non-selective cation channel in the plasma membrane that is involved in the innate immune response regulating, for example, chemotaxis in neutrophils and cytokine secretion in...
3.
Danyukova T, Alimy A, Velho R, Yorgan T, Di Lorenzo G, von Kroge S, et al.
Bone
. 2023 Oct;
177:116927.
PMID: 37797712
Missense variants in the MBTPS2 gene, located on the X chromosome, have been associated with an X-linked recessive form of osteogenesis imperfecta (X-OI), an inherited bone dysplasia characterized by multiple...
4.
Chan D, Josts I, Koteva K, Wright G, Tidow H, Burrows L
Proc Natl Acad Sci U S A
. 2023 Apr;
120(16):e2221253120.
PMID: 37043535
The outer membrane of gram-negative bacteria prevents many antibiotics from reaching intracellular targets. However, some antimicrobials can take advantage of iron import transporters to cross this barrier. We showed previously...
5.
Josts I, Kehlenbeck D, Nitsche J, Tidow H
Methods Enzymol
. 2022 Nov;
677:417-432.
PMID: 36410958
Structural studies of integral membrane proteins (IMPs) are challenging as many of them require a lipid environment for full activity and stability. Reconstitution of IMPs into carrier systems such as...
6.
Tidow H, Josts I
Methods Enzymol
. 2022 Nov;
677:251-262.
PMID: 36410951
Protein function is highly dependent on conformational changes and association or dissociation into numerous oligomeric states. Stopped-flow approaches are suitable for probing transient kinetics in proteins, and combining this approach...
7.
Sander S, Muller I, Garcia-Alai M, Nicke A, Tidow H
J Biol Chem
. 2022 Sep;
298(10):102495.
PMID: 36115462
P2X7 receptors are nonselective cation channels that are activated by extracellular ATP and play important roles in inflammation. They differ from other P2X family members by a large intracellular C-terminus...
8.
Sander S, Pick J, Gattkowski E, Fliegert R, Tidow H
Protein Sci
. 2022 May;
31(6):e4320.
PMID: 35634784
Transient receptor potential melastatin 2 (TRPM2) is a Ca -permeable, nonselective cation channel involved in diverse physiological processes such as immune response, apoptosis, and body temperature sensing. TRPM2 is activated...
9.
Riekehr W, Sander S, Pick J, Tidow H, Bauche A, Guse A, et al.
Int J Mol Sci
. 2022 Mar;
23(6).
PMID: 35328585
cADPR is a second messenger that releases Ca from intracellular stores via the ryanodine receptor. Over more than 15 years, it has been controversially discussed whether cADPR also contributes to...
10.
Ruppert M, Creon A, Tidow H, Huse N
J Phys Chem B
. 2022 Jan;
126(2):368-375.
PMID: 34990136
We genetically incorporated the unnatural amino acid p-azido-phenylalanine (AzF) into the ubiquitous Ca sensor protein calmodulin (CaM) in complex with different peptides to explore the response of the azido stretching...