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Simon Sander

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Articles 8
Citations 45
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Recent Articles
1.
Goradia N, Werner S, Mullapudi E, Greimeier S, Bergmann L, Lang A, et al.
Nat Commun . 2024 Jun; 15(1):5241. PMID: 38898011
While the elucidation of regulatory mechanisms of folded proteins is facilitated due to their amenability to high-resolution structural characterization, investigation of these mechanisms in disordered proteins is more challenging due...
2.
Pick J, Sander S, Etzold S, Rosche A, Tidow H, Guse A, et al.
Front Immunol . 2024 Feb; 15:1294357. PMID: 38318185
TRPM2 is a Ca permeable, non-selective cation channel in the plasma membrane that is involved in the innate immune response regulating, for example, chemotaxis in neutrophils and cytokine secretion in...
3.
Sander S, Muller I, Garcia-Alai M, Nicke A, Tidow H
J Biol Chem . 2022 Sep; 298(10):102495. PMID: 36115462
P2X7 receptors are nonselective cation channels that are activated by extracellular ATP and play important roles in inflammation. They differ from other P2X family members by a large intracellular C-terminus...
4.
Sander S, Pick J, Gattkowski E, Fliegert R, Tidow H
Protein Sci . 2022 May; 31(6):e4320. PMID: 35634784
Transient receptor potential melastatin 2 (TRPM2) is a Ca -permeable, nonselective cation channel involved in diverse physiological processes such as immune response, apoptosis, and body temperature sensing. TRPM2 is activated...
5.
Riekehr W, Sander S, Pick J, Tidow H, Bauche A, Guse A, et al.
Int J Mol Sci . 2022 Mar; 23(6). PMID: 35328585
cADPR is a second messenger that releases Ca from intracellular stores via the ryanodine receptor. Over more than 15 years, it has been controversially discussed whether cADPR also contributes to...
6.
Kehlenbeck D, Traore D, Josts I, Sander S, Moulin M, Haertlein M, et al.
FEBS J . 2021 Dec; 289(10):2959-2970. PMID: 34921499
The ATP-binding cassette transporter MsbA is a lipid flippase, translocating lipid A, glycolipids, and lipopolysaccharides from the inner to the outer leaflet of the inner membrane of Gram-negative bacteria. It...
7.
Gattkowski E, Rutherford T, Mockl F, Bauche A, Sander S, Fliegert R, et al.
FEBS J . 2021 Jun; 288(23):6769-6782. PMID: 34189846
Nudix hydrolase 9 (NUDT9) is a member of the nucleoside linked to another moiety X (NUDIX) protein superfamily, which hydrolyses a broad spectrum of organic pyrophosphates from metabolic processes. ADP-ribose...
8.
Niebling S, Burastero O, Burgi J, Gunther C, Defelipe L, Sander S, et al.
Sci Rep . 2021 May; 11(1):9572. PMID: 33953265
Differential scanning fluorimetry (DSF) using the inherent fluorescence of proteins (nDSF) is a popular technique to evaluate thermal protein stability in different conditions (e.g. buffer, pH). In many cases, ligand...