Gary L Johnson
Overview
Explore the profile of Gary L Johnson including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
162
Citations
6908
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kakati R, Whitman A, Haase S, Szenasi A, Thai C, Brunk E, et al.
bioRxiv
. 2025 Feb;
PMID: 39975402
Significance: Vandetanib enhances sensitivity to tamoxifen in ER+ breast cancer cells by reprograming kinase signaling networks, which can be used to select patients most likely to respond and develop more...
2.
Matkar S, East M, Stuhlmiller T, Witek G, Farrel A, Pastor S, et al.
Mol Cancer Ther
. 2025 Feb;
PMID: 39907037
Mutations in the tyrosine kinase domain of the Anaplastic Lymphoma Kinase (ALK) oncogene in neuroblastoma occur most frequently at one of three hotspot amino acid residues, with the F1174* and...
3.
Prasath V, Boutrid H, Wesolowski R, Abdel-Rasoul M, Timmers C, Lustberg M, et al.
Breast Cancer Res Treat
. 2024 Dec;
210(1):179-189.
PMID: 39644403
Purpose: While MEK inhibitors demonstrated activity in metastatic triple negative breast cancer (mTNBC) preclinical studies, preclinical, and clinical studies implicate rapid development of resistance limiting clinical benefit. The purpose of...
4.
Xu Y, Peng X, East M, McCabe I, Stroman G, Jenner M, et al.
Cancer Discov
. 2024 Dec;
15(2):346-362.
PMID: 39632628
We provide a comprehensive tumor-intrinsic kinome landscape that provides a roadmap for the use of kinase inhibitors in PDAC treatment approaches.
5.
East M, Sprung R, Okumu D, Olivares-Quintero J, Joisa C, Chen X, et al.
bioRxiv
. 2024 Oct;
PMID: 39464086
The kinome is a dynamic system of kinases regulating signaling networks in cells and dysfunction of protein kinases contributes to many diseases. Regulation of the protein expression of kinases alters...
6.
Berginski M, Jenner M, Joisa C, Herrera Loeza G, Golitz B, Lipner M, et al.
PeerJ
. 2024 Sep;
12:e17797.
PMID: 39221276
Numerous aspects of cellular signaling are regulated by the kinome-the network of over 500 protein kinases that guides and modulates information transfer throughout the cell. The key role played by...
7.
DuBose E, Bevill S, Mitchell D, Sciaky N, Golitz B, Dixon S, et al.
Front Oncol
. 2024 Jun;
14:1191217.
PMID: 38854737
Introduction: Approximately 50% of melanomas harbor an activating mutation. Standard of care involves a combination of inhibitors targeting mutant BRAF and MEK1/2, the substrate for BRAF in the MAPK pathway....
8.
Flint A, Mitchell D, Angus S, Smith A, Bessler W, Jiang L, et al.
Clin Cancer Res
. 2024 May;
30(9):1992.
PMID: 38690594
No abstract available.
9.
Karim M, Mishra M, Lo C, Saul S, Cagirici H, Nhu Tran D, et al.
bioRxiv
. 2024 Apr;
PMID: 38659941
In search for broad-spectrum antivirals, we discovered a small molecule inhibitor, RMC-113, that potently suppresses the replication of multiple RNA viruses including SARS-CoV-2 in human lung organoids. We demonstrated selective...
10.
Asquith C, East M, Laitinen T, Alamillo-Ferrer C, Hartikainen E, Wells C, et al.
Eur J Med Chem
. 2024 Apr;
271:116357.
PMID: 38636130
The oxindole scaffold has been the center of several kinase drug discovery programs, some of which have led to approved medicines. A series of two oxindole matched pairs from the...