Amy N Abell
Overview
Explore the profile of Amy N Abell including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
25
Citations
1397
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Nelson H, Mullins N, Abell A
J Biol Chem
. 2024 Dec;
301(2):108116.
PMID: 39710325
Mitogen-activated protein kinase kinase kinase 4 (MAP3K4) promotes fetal and placental growth and development, with MAP3K4 kinase inactivation resulting in placental insufficiency and fetal growth restriction. MAP3K4 promotes key signaling...
2.
Perkins R, Singh R, Abell A, Krum S, Miranda-Carboni G
Front Cell Dev Biol
. 2023 Feb;
11:1120365.
PMID: 36814601
WNT10B, a member of the WNT family of secreted glycoproteins, activates the WNT/β-catenin signaling cascade to control proliferation, stemness, pluripotency, and cell fate decisions. WNT10B plays roles in many tissues,...
3.
Hollis P, Mobley R, Bhuju J, Abell A, Sutter C, Sutter T
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36077068
Cytochrome P4501B1 (CYP1B1) is elevated in breast cancer. Studies indicate a relationship between CYP1B1 and aggressive cancer phenotypes. Here, we report on in vitro studies in triple-negative breast cancer cell...
4.
Perry C, Mullins N, Sweileh R, Shendy N, Roberto P, Broadhurst A, et al.
J Biol Chem
. 2022 Aug;
298(9):102310.
PMID: 35921893
Disruption of fetal growth results in severe consequences to human health, including increased fetal and neonatal morbidity and mortality, as well as potential lifelong health problems. Molecular mechanisms promoting fetal...
5.
Shendy N, Broadhurst A, Shoemaker K, Read R, Abell A
Biol Reprod
. 2021 Apr;
105(2):491-502.
PMID: 33912929
Sex determination requires the commitment of bipotential gonads to either a testis or an ovarian fate. Gene deletion of the kinase Map3k4 results in gonadal sex reversal in XY mice,...
6.
Raghu D, Mobley R, Shendy N, Perry C, Abell A
Cell Rep
. 2019 Mar;
26(13):3684-3697.e7.
PMID: 30917321
O-GalNAc glycosylation is initiated in the Golgi by glycosyltransferases called GALNTs. Proteomic screens identified >600 O-GalNAc-modified proteins, but the biological relevance of these modifications has been difficult to determine. We...
7.
Mobley R, Abell A
J Nat Sci
. 2017 Sep;
3(9).
PMID: 28936481
Large-scale epigenetic changes take place when epithelial cells with cell-cell adhesion and apical-basal polarity transition into invasive, individual, mesenchymal cells through a process known as epithelial to mesenchymal transition (EMT)....
8.
Mobley R, Raghu D, Duke L, Abell-Hart K, Zawistowski J, Lutz K, et al.
Cell Rep
. 2017 Mar;
18(10):2387-2400.
PMID: 28273454
The first epithelial-to-mesenchymal transition (EMT) occurs in trophoblast stem (TS) cells during implantation. Inactivation of the serine/threonine kinase MAP3K4 in TS cells (TS cells) induces an intermediate state of EMT,...
9.
Abell A, Johnson G
Curr Pathobiol Rep
. 2014 Dec;
2(1):21-26.
PMID: 25530923
The epithelial to mesenchymal transition (EMT) generates tumor cells having stem cell characteristics with phenotypes similar to cancer stem cells (CSCs). Evidence suggests CSCs are in an intermediate state of...
10.
Vincent Jordan N, Prat A, Abell A, Zawistowski J, Sciaky N, Karginova O, et al.
Mol Cell Biol
. 2013 May;
33(15):3011-25.
PMID: 23716599
We previously identified a gene signature predicted to regulate the epithelial-mesenchymal transition (EMT) in both epithelial tissue stem cells and breast cancer cells. A phenotypic RNA interference (RNAi) screen identified...