Gabriel E Zentner
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Explore the profile of Gabriel E Zentner including associated specialties, affiliations and a list of published articles.
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58
Citations
2435
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Recent Articles
1.
Mahmoudzadeh N, Heidarian Y, Tourigny J, Fitt A, Beebe K, Li H, et al.
Mol Metab
. 2024 Aug;
89:102013.
PMID: 39182840
Objectives: The mitochondrial enzyme L-2-hydroxyglutarate dehydrogenase (L2HGDH) regulates the abundance of L-2-hydroxyglutarate (L-2HG), a potent signaling metabolite capable of influencing chromatin architecture, mitochondrial metabolism, and cell fate decisions. Loss of...
2.
Markley H, Helms K, Maar M, Zentner G, Wade M, Zelhof A
J Insect Sci
. 2024 Aug;
24(4).
PMID: 39162172
CRISPR/Cas9 manipulations are possible in many insects and ever expanding. Nonetheless, success in one species and techniques developed for it are not necessarily applicable to other species. As such, the...
3.
Rai M, Li H, Policastro R, Zentner G, Nemkov T, DAlessandro A, et al.
bioRxiv
. 2024 Jun;
PMID: 38895259
larval growth requires efficient conversion of dietary nutrients into biomass. Lactate Dehydrogenase (Ldh) and Glycerol-3-phosphate dehydrogenase (Gpdh1) support larval biosynthetic metabolism by maintaining NAD/NADH redox balance and promoting glycolytic flux....
4.
Anand R, Layer J, Heja D, Hirose T, Lassiter G, Firl D, et al.
Nature
. 2023 Oct;
622(7982):393-401.
PMID: 37821590
Recent human decedent model studies and compassionate xenograft use have explored the promise of porcine organs for human transplantation. To proceed to human studies, a clinically ready porcine donor must...
5.
Saleh M, Hundley H, Zentner G
G3 (Bethesda)
. 2022 Nov;
12(12).
PMID: 36331351
Regulation of RNA polymerase II transcription requires the concerted efforts of several multisubunit coactivator complexes, which interact with the RNA polymerase II preinitiation complex to stimulate transcription. We previously showed...
6.
Ding L, Zentner G, McDonald D
Bioinform Adv
. 2022 Jun;
2(1):vbac033.
PMID: 35722206
Motivation: Methods for the global measurement of transcript abundance such as microarrays and RNA-Seq generate datasets in which the number of measured features far exceeds the number of observations. Extracting...
7.
Policastro R, Zentner G
Methods Mol Biol
. 2022 May;
2477:21-34.
PMID: 35524109
Transcription start site (TSS) usage is a critical factor in the regulation of gene expression. A number of methods for global TSS mapping have been developed, but barriers of expense,...
8.
Rylee J, Nin-Velez A, Mahato S, Helms K, Wade M, Zentner G, et al.
Insect Mol Biol
. 2022 Apr;
31(5):543-550.
PMID: 35429082
CRISPR/Cas9 genome editing has now expanded to many insect species, including Tribolium castaneum. However, compared to Drosophila melanogaster, the CRISPR toolkit of T. castaneum is limited. A particularly apparent gap...
9.
Zentner G
Mol Cell
. 2021 Nov;
81(22):4574-4576.
PMID: 34798043
Gopalan et al. (2021) present multi-CUT&Tag, a modification of cleavage under targets and tagmentation (CUT&Tag) that enables simultaneous genome-wide mapping of multiple chromatin-associated targets in a single sample.
10.
Policastro R, Zentner G
Cell Rep Methods
. 2021 Oct;
1(5).
PMID: 34632443
Transcription start site (TSS) selection influences transcript stability and translation as well as protein sequence. Alternative TSS usage is pervasive in organismal development, is a major contributor to transcript isoform...