Peter C Scacheri
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Explore the profile of Peter C Scacheri including associated specialties, affiliations and a list of published articles.
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82
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4930
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Recent Articles
1.
Sullivan K, Kainer D, Lane M, Cashman M, Miller J, Garvin M, et al.
Biol Psychiatry
. 2024 Nov;
PMID: 39615775
Background: Opioid addiction is a worldwide public health crisis. In the United States, for example, opioids cause more drug overdose deaths than any other substance. However, opioid addiction treatments have...
2.
Drew D, Kim A, Lin Y, Qu C, Morrison J, Lewinger J, et al.
Sci Adv
. 2024 May;
10(22):eadk3121.
PMID: 38809988
Regular, long-term aspirin use may act synergistically with genetic variants, particularly those in mechanistically relevant pathways, to confer a protective effect on colorectal cancer (CRC) risk. We leveraged pooled data...
3.
Chen Z, Guo X, Tao R, Huyghe J, Law P, Fernandez-Rozadilla C, et al.
Nat Commun
. 2024 Apr;
15(1):3557.
PMID: 38670944
Genome-wide association studies (GWAS) have identified more than 200 common genetic variants independently associated with colorectal cancer (CRC) risk, but the causal variants and target genes are mostly unknown. We...
4.
Pontius W, Hong E, Faber Z, Gray J, Peacock C, Bayles I, et al.
Nat Commun
. 2023 Nov;
14(1):7209.
PMID: 37938582
The metastasis-invasion cascade describes the series of steps required for a cancer cell to successfully spread from its primary tumor and ultimately grow within a secondary organ. Despite metastasis being...
5.
Dimou N, Kim A, Flanagan O, Murphy N, Diez-Obrero V, Shcherbina A, et al.
Br J Cancer
. 2023 Jun;
129(3):511-520.
PMID: 37365285
Background: Diabetes is an established risk factor for colorectal cancer. However, the mechanisms underlying this relationship still require investigation and it is not known if the association is modified by...
6.
Aglago E, Kim A, Lin Y, Qu C, Evangelou M, Ren Y, et al.
Cancer Res
. 2023 May;
83(15):2572-2583.
PMID: 37249599
Significance: This gene-environment interaction analysis revealed a genetic locus in FMN1/GREM1 that interacts with body mass index in colorectal cancer risk, suggesting potential implications for precision prevention strategies.
7.
Qu D, Neu D, Khawaja Z, Wang R, Bartels C, Lovrenert K, et al.
J Transl Genet Genom
. 2023 Feb;
7(1):3-16.
PMID: 36817228
Aim: Obesity and obesogenic diets might partly accelerate cancer development through epigenetic mechanisms. To determine these early effects, we investigated the impact of three days of a high-fat diet on...
8.
Carreras-Torres R, Kim A, Lin Y, Diez-Obrero V, Bien S, Qu C, et al.
Cancer Epidemiol Biomarkers Prev
. 2022 Dec;
32(3):315-328.
PMID: 36576985
Background: Tobacco smoking is an established risk factor for colorectal cancer. However, genetically defined population subgroups may have increased susceptibility to smoking-related effects on colorectal cancer. Methods: A genome-wide interaction...
9.
Jordahl K, Shcherbina A, Kim A, Su Y, Lin Y, Wang J, et al.
Cancer Epidemiol Biomarkers Prev
. 2022 Apr;
31(5):1077-1089.
PMID: 35438744
Background: Currently known associations between common genetic variants and colorectal cancer explain less than half of its heritability of 25%. As alcohol consumption has a J-shape association with colorectal cancer...
10.
Corradin O, Sallari R, Hoang A, Kassim B, Ben Hutta G, Cuoto L, et al.
Mol Psychiatry
. 2022 Mar;
27(4):2158-2170.
PMID: 35301427
Opioid use disorder is a highly heterogeneous disease driven by a variety of genetic and environmental risk factors which have yet to be fully elucidated. Opioid overdose, the most severe...