Gabriel Bricard
Overview
Explore the profile of Gabriel Bricard including associated specialties, affiliations and a list of published articles.
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23
Citations
582
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Recent Articles
1.
Bricard G, Cadassou O, Cassagnes L, Cros-Perrial E, Payen-Gay L, Puy J, et al.
Oncotarget
. 2017 Oct;
8(40):67380-67393.
PMID: 28978040
The cytosolic 5'-nucleotidase cN-II is a highly conserved enzyme implicated in nucleotide metabolism. Based on recent observations suggesting additional roles not directly associated to its enzymatic activity, we studied human...
2.
Bricard G, Cros-Perrial E, Machon C, Dumontet C, Jordheim L
Nucleosides Nucleotides Nucleic Acids
. 2016 Dec;
35(10-12):604-612.
PMID: 27906612
The 5'-nucleotidase cN-II has been shown to be associated with the sensitivity to nucleoside analogues, the survival of cytarabine treated leukemia patients and to cell proliferation. Due to the lack...
3.
Bachy E, Urb M, Chandra S, Robinot R, Bricard G, de Bernard S, et al.
J Exp Med
. 2016 Apr;
213(5):841-57.
PMID: 27069116
Peripheral T cell lymphomas (PTCLs) are a heterogeneous entity of neoplasms with poor prognosis, lack of effective therapies, and a largely unknown pathophysiology. Identifying the mechanism of lymphomagenesis and cell-of-origin...
4.
OReilly V, Zeng S, Bricard G, Atzberger A, Hogan A, Jackson J, et al.
PLoS One
. 2011 Dec;
6(12):e28648.
PMID: 22174854
CD1d-restricted invariant natural killer T (iNKT) cells have diverse immune stimulatory/regulatory activities through their ability to release cytokines and to kill or transactivate other cells. Activation of iNKT cells can...
5.
Roujeau J, Bricard G, Nicolas J
J Allergy Clin Immunol
. 2011 Dec;
128(6):1277-8.
PMID: 22133320
No abstract available.
6.
Arora P, Venkataswamy M, Baena A, Bricard G, Li Q, Veerapen N, et al.
J Am Chem Soc
. 2011 Mar;
133(14):5198-201.
PMID: 21425779
Structural variants of α-galactosylceramide (αGC) that activate invariant natural killer T cells (iNKT cells) are being developed as potential immunomodulatory agents for a variety of applications. Identification of specific forms...
7.
Bricard G, Venkataswamy M, Yu K, Im J, Ndonye R, Howell A, et al.
PLoS One
. 2010 Dec;
5(12):e14374.
PMID: 21179412
CD1d-restricted natural killer T cells with invariant T cell receptor α chains (iNKT cells) are a unique lymphocyte subset that responds to recognition of specific lipid and glycolipid antigens. They...
8.
Jervis P, Veerapen N, Bricard G, Cox L, Porcelli S, Besra G
Bioorg Med Chem Lett
. 2010 Jun;
20(12):3475-8.
PMID: 20529677
Alpha-glucosyl ceramides 4 and 5 have been synthesised and evaluated for their ability to stimulate the activation and expansion of human iNKT cells. The key challenge in the synthesis of...
9.
Veerapen N, Reddington F, Bricard G, Porcelli S, Besra G
Bioorg Med Chem Lett
. 2010 May;
20(11):3223-6.
PMID: 20462758
Several L-fucoglycolipids are associated with diseases such as cancer, cystic fibrosis and rheumatoid arthritis. Activation of iNKT cells is known to lead to the production of cytokines that can help...
10.
Park J, Lee J, Seo K, Bricard G, Venkataswamy M, Porcelli S, et al.
Bioorg Med Chem Lett
. 2010 Jan;
20(3):814-8.
PMID: 20061147
KRN7000 is an important ligand identified for CD1d protein of APC, and KRN7000/CD1d complex can stimulate NKT cells to release a broad range of bioactive cytokines. In an effort to...