Frederick C K Wong
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Explore the profile of Frederick C K Wong including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
313
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Recent Articles
1.
Mareckova M, Garcia-Alonso L, Moullet M, Lorenzi V, Petryszak R, Sancho-Serra C, et al.
Nat Genet
. 2024 Aug;
56(9):1925-1937.
PMID: 39198675
The complex and dynamic cellular composition of the human endometrium remains poorly understood. Previous endometrial single-cell atlases profiled few donors and lacked consensus in defining cell types. We introduce the...
2.
Xue X, Kim Y, Ponce-Arias A, OLaughlin R, Yan R, Kobayashi N, et al.
Nature
. 2024 Feb;
628(8007):391-399.
PMID: 38408487
The human nervous system is a highly complex but organized organ. The foundation of its complexity and organization is laid down during regional patterning of the neural tube, the embryonic...
3.
Alves-Lopes J, Wong F, Surani M
Nat Protoc
. 2024 Feb;
19(4):1149-1182.
PMID: 38302732
Human primordial germ cells (hPGCs), the precursors of eggs and sperm, start their complex development shortly after specification and during their migration to the primitive gonads. Here, we describe protocols...
4.
Arutyunyan A, Roberts K, Troule K, Wong F, Sheridan M, Kats I, et al.
Nature
. 2023 Mar;
616(7955):143-151.
PMID: 36991123
The relationship between the human placenta-the extraembryonic organ made by the fetus, and the decidua-the mucosal layer of the uterus, is essential to nurture and protect the fetus during pregnancy....
5.
Gruhn W, Tang W, Dietmann S, Alves-Lopes J, Penfold C, Wong F, et al.
Sci Adv
. 2023 Jan;
9(3):eade1257.
PMID: 36652508
Epigenetic resetting in the mammalian germ line entails acute DNA demethylation, which lays the foundation for gametogenesis, totipotency, and embryonic development. We characterize the epigenome of hypomethylated human primordial germ...
6.
Alves-Lopes J, Wong F, Tang W, Gruhn W, Ramakrishna N, Jowett G, et al.
Cell Rep
. 2023 Jan;
42(1):111907.
PMID: 36640324
Human primordial germ cells (hPGCs), the precursors of sperm and eggs, are specified during weeks 2-3 after fertilization. Few studies on ex vivo and in vitro cultured human embryos reported...
7.
Wong F
Methods Mol Biol
. 2020 Sep;
2214:143-155.
PMID: 32944908
Immunofluorescence staining enables the visualization of protein expression at a cellular or even sub-nuclear level. Whole-mount staining preserves the three-dimensional spatial information in biological samples allowing a comprehensive interpretation of...
8.
Neupane J, Wong F, Surani M
Cell Res
. 2020 Jan;
30(2):103-104.
PMID: 31913357
No abstract available.
9.
Pierson Smela M, Sybirna A, Wong F, Surani M
Wellcome Open Res
. 2019 Oct;
4:122.
PMID: 31583280
Potentially novel regulators of early human germline development have been identified recently, including SOX15 and SOX17, both of which show specific expression in human primordial germ cells. SOX17 is now...
10.
Sybirna A, Wong F, Surani M
Curr Top Dev Biol
. 2019 Jun;
135:35-89.
PMID: 31155363
Primordial germ cells (PGCs) are embryonic precursors of sperm and egg that pass on genetic and epigenetic information from one generation to the next. In mammals, they are induced from...