Navin B Ramakrishna
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Explore the profile of Navin B Ramakrishna including associated specialties, affiliations and a list of published articles.
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10
Citations
129
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Recent Articles
1.
Saredi G, Carelli F, Rolland S, Furlan G, Piquet S, Appert A, et al.
Nat Struct Mol Biol
. 2024 Jan;
31(3):523-535.
PMID: 38238586
Histone chaperones control nucleosome density and chromatin structure. In yeast, the H3-H4 chaperone Spt2 controls histone deposition at active genes but its roles in metazoan chromatin structure and organismal physiology...
2.
Gruhn W, Tang W, Dietmann S, Alves-Lopes J, Penfold C, Wong F, et al.
Sci Adv
. 2023 Jan;
9(3):eade1257.
PMID: 36652508
Epigenetic resetting in the mammalian germ line entails acute DNA demethylation, which lays the foundation for gametogenesis, totipotency, and embryonic development. We characterize the epigenome of hypomethylated human primordial germ...
3.
Alves-Lopes J, Wong F, Tang W, Gruhn W, Ramakrishna N, Jowett G, et al.
Cell Rep
. 2023 Jan;
42(1):111907.
PMID: 36640324
Human primordial germ cells (hPGCs), the precursors of sperm and eggs, are specified during weeks 2-3 after fertilization. Few studies on ex vivo and in vitro cultured human embryos reported...
4.
Ramakrishna N, Battistoni G, Surani M, Hannon G, Miska E
Dev Cell
. 2022 Dec;
57(23):2661-2668.e5.
PMID: 36473462
PIWI-interacting RNAs (piRNAs) are small RNAs bound by PIWI-clade Argonaute proteins that function to silence transposable elements (TEs). Following mouse primordial germ cell (mPGC) specification around E6.25, fetal piRNAs emerge...
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6.
Ramakrishna N, Murison K, Miska E, Leitch H
Sex Dev
. 2021 Nov;
15(5-6):411-431.
PMID: 34847550
Germline development varies significantly across metazoans. However, mammalian primordial germ cell (PGC) development has key conserved landmarks, including a critical period of epigenetic reprogramming that precedes sex-specific differentiation and gametogenesis....
7.
Dallaire A, Manley B, Wilkens M, Bista I, Quan C, Evangelisti E, et al.
Genome Res
. 2021 Nov;
31(12):2290-2302.
PMID: 34772700
Arbuscular mycorrhizal (AM) fungi form mutualistic relationships with most land plant species. AM fungi have long been considered as ancient asexuals. Long-term clonal evolution would be remarkable for a eukaryotic...
8.
Ramakrishna N, Miska E
Dev Cell
. 2021 Aug;
56(16):2269-2270.
PMID: 34428395
Instead of causing immediate sterility, loss of the C. elegans PIWI protein PRG-1 leads to accumulated infertility after tens of generations. In this issue of Developmental Cell, Wahba et al....
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10.
Ho L, Tan S, Wee S, Wu Y, Tan S, Ramakrishna N, et al.
Cell Stem Cell
. 2015 Sep;
17(4):435-47.
PMID: 26387754
ELABELA (ELA) is a peptide hormone required for heart development that signals via the Apelin Receptor (APLNR, APJ). ELA is also abundantly secreted by human embryonic stem cells (hESCs), which...