Joao Pedro Alves-Lopes
Overview
Explore the profile of Joao Pedro Alves-Lopes including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
9
Citations
269
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Cui Y, Harteveld F, Ba Omar H, Yang Y, Bjarnason R, Romerius P, et al.
Hum Reprod Open
. 2024 Aug;
2024(3):hoae049.
PMID: 39188568
Study Question: Can human pre- and peri-pubertal testicular cells obtained from childhood cancer patients, previously treated with chemotherapy, form testicular organoids (TOs)? Summary Answer: Organoid formation from testicular tissue collected...
2.
Alves-Lopes J, Wong F, Surani M
Nat Protoc
. 2024 Feb;
19(4):1149-1182.
PMID: 38302732
Human primordial germ cells (hPGCs), the precursors of eggs and sperm, start their complex development shortly after specification and during their migration to the primitive gonads. Here, we describe protocols...
3.
Alves-Lopes J, Wong F, Tang W, Gruhn W, Ramakrishna N, Jowett G, et al.
Cell Rep
. 2023 Jan;
42(1):111907.
PMID: 36640324
Human primordial germ cells (hPGCs), the precursors of sperm and eggs, are specified during weeks 2-3 after fertilization. Few studies on ex vivo and in vitro cultured human embryos reported...
4.
Garcia-Alonso L, Lorenzi V, Mazzeo C, Alves-Lopes J, Roberts K, Sancho-Serra C, et al.
Nature
. 2022 Jul;
607(7919):540-547.
PMID: 35794482
Gonadal development is a complex process that involves sex determination followed by divergent maturation into either testes or ovaries. Historically, limited tissue accessibility, a lack of reliable in vitro models...
5.
Oliver E, Alves-Lopes J, Harteveld F, Mitchell R, Akesson E, Soder O, et al.
BMC Biol
. 2021 Sep;
19(1):212.
PMID: 34556114
Background: Advances in three-dimensional culture technologies have led to progression in systems used to model the gonadal microenvironment in vitro. Despite demonstrating basic functionality, tissue organisation is often limited. We...
6.
Kurek M, Akesson E, Yoshihara M, Oliver E, Cui Y, Becker M, et al.
Cells
. 2021 Jan;
10(2).
PMID: 33513766
Fertility preservation for male childhood cancer survivors not yet capable of producing mature spermatozoa, relies on experimental approaches such as testicular explant culture. Although the first steps in somatic maturation...
7.
Alves-Lopes J, Soder O, Stukenborg J
Nat Protoc
. 2018 Jan;
13(2):248-259.
PMID: 29300391
We have recently developed a 3D culture system that allows the reorganization of rat primary testicular cells into organoids with a functional blood-testis barrier, as well as the establishment and...
8.
Alves-Lopes J, Stukenborg J
Hum Reprod Update
. 2017 Dec;
24(2):176-191.
PMID: 29281008
Background: In recent decades, a broad range of strategies have been applied to model the testicular microenvironment in vitro. These models have been utilized to study testicular physiology and development....
9.
Alves-Lopes J, Soder O, Stukenborg J
Biomaterials
. 2017 Apr;
130:76-89.
PMID: 28364632
A system that models the testicular microenvironment and spermatogonial stem-cell (SSC) niche in vitro has not been produced yet. Here, we developed and characterized a novel three-dimensional multilayer model, the...