Frantisek Papousek
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Explore the profile of Frantisek Papousek including associated specialties, affiliations and a list of published articles.
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25
Citations
389
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Recent Articles
1.
Hojna S, Malinska H, Huttl M, Vanourkova Z, Markova I, Miklankova D, et al.
Biomed Pharmacother
. 2024 Apr;
174:116520.
PMID: 38581924
A combination of liver and heart dysfunction worsens the prognosis of human survival. The aim of this study was to investigate whether empagliflozin (a sodium-glucose transporter-2 inhibitor) has beneficial effects...
2.
Huskova Z, Kikerlova S, Miklovic M, Kala P, Papousek F, Neckar J
Front Physiol
. 2023 Jun;
14:1151308.
PMID: 37389123
The aim of the study was to clarify the role of the interplay between hypertension and the renin-angiotensin system (RAS) in the pathophysiology of myocardial ischemia/reperfusion (I/R) injury. We hypothesized...
3.
Hrabalova P, Bohuslavova R, Matejkova K, Papousek F, Sedmera D, Abaffy P, et al.
Cardiovasc Diabetol
. 2023 Apr;
22(1):88.
PMID: 37072781
Background: An altered sympathetic nervous system is implicated in many cardiac pathologies, ranging from sudden infant death syndrome to common diseases of adulthood such as hypertension, myocardial ischemia, cardiac arrhythmias,...
4.
Malinska H, Huttl M, Markova I, Miklankova D, Hojna S, Papousek F, et al.
Biomedicines
. 2022 Sep;
10(9).
PMID: 36140169
Gliflozins (inhibitors of sodium-glucose cotransporter 2) show many beneficial actions beyond their antidiabetic effects. The underlying mechanisms of these additional protective effects are still not well understood, especially under non-diabetic...
5.
Markovic A, Tauchmannova K, Simakova M, Mlejnek P, Kaplanova V, Pecina P, et al.
Biomedicines
. 2022 Feb;
10(2).
PMID: 35203486
Mutations of the gene disrupt the biogenesis of the ATP synthase and represent the most frequent cause of autosomal recessive encephalo-cardio-myopathy with neonatal onset. Patient tissues show isolated defects in...
6.
Hojna S, Rauchova H, Malinska H, Markova I, Huttl M, Papousek F, et al.
Biomed Pharmacother
. 2021 Oct;
144:112246.
PMID: 34601191
The new antidiabetic drugs, gliflozins, inhibit sodium-glucose transporter-2 in renal proximal tubules promoting glucose and sodium excretion. This leads not only to a significant improvement of glucose control but also...
7.
Neckar J, Alanova P, Olejnickova V, Papousek F, Hejnova L, Silhavy J, et al.
Clin Sci (Lond)
. 2021 Sep;
135(17):2143-2163.
PMID: 34486670
Increased level of C-reactive protein (CRP) is a risk factor for cardiovascular diseases, including myocardial infarction and hypertension. Here, we analyzed the effects of CRP overexpression on cardiac susceptibility to...
8.
Huskova Z, Kikerlova S, Sadowski J, Alanova P, Sedlakova L, Papousek F, et al.
Front Pharmacol
. 2021 Jun;
12:679060.
PMID: 34122103
We investigated the role of the interaction between hypertension and the renin-angiotensin system in the pathophysiology of myocardial ischemia/reperfusion injury. We hypothesized that in the early phase of angiotensin II...
9.
Papousek F, Sedmera D, Neckar J, Ostadal B, Kolar F
Respir Physiol Neurobiol
. 2020 Aug;
282:103526.
PMID: 32805421
The main aim was to find out whether long-lasting stepwise exposure to extreme hypoxia affects left ventricular (LV) geometry and systolic function. Adult male rats were exposed to intermittent hypobaric...
10.
Bohuslavova R, Cerychova R, Papousek F, Olejnickova V, Bartos M, Gorlach A, et al.
Proc Natl Acad Sci U S A
. 2019 Jun;
116(27):13414-13423.
PMID: 31196952
The molecular mechanisms regulating sympathetic innervation of the heart during embryogenesis and its importance for cardiac development and function remain to be fully elucidated. We generated mice in which conditional...