Olga Novakova
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Explore the profile of Olga Novakova including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Novakov V, Novakova O, Churnosova M, Aristova I, Ponomarenko M, Reshetnikova Y, et al.
Arthroplasty
. 2024 Feb;
6(1):12.
PMID: 38424630
Background: We investigated the effect of obesity on the association of genome-wide associative studies (GWAS)-significant genes with the risk of knee osteoarthritis (KOA). Methods: All study participants (n = 1,100)...
2.
Sevela S, Meisnerova E, Vecka M, Vavrova L, Rychlikova J, Lenicek M, et al.
Nutrients
. 2024 Feb;
16(4).
PMID: 38398809
(1) Objectives Intestinal failure in home parenteral nutrition patients (HPNPs) results in oxidative stress and liver damage. This study investigated how a high dose of fish oil (FO) added to...
3.
Marvanova A, Kasik P, Elsnicova B, Tibenska V, Galatik F, Hornikova D, et al.
Sci Rep
. 2023 Oct;
13(1):18287.
PMID: 37880253
Moderate cold acclimation (MCA) is a non-invasive intervention mitigating effects of various pathological conditions including myocardial infarction. We aim to determine the shortest cardioprotective regimen of MCA and the response...
4.
Kostrhunova H, McGhie B, Markova L, Novakova O, Kasparkova J, Aldrich-Wright J, et al.
J Med Chem
. 2023 Jun;
66(12):7894-7908.
PMID: 37285472
The platinum(II) complex [Pt(1,2S-diaminocyclohexane)(5,6-dimethyl-1,10-phenanthroline)] (Pt56MeSS, ) exhibits high potency across numerous cancer cell lines acting by a multimodal mechanism. However, also displays side toxicity and in vivo activity; all details...
5.
Novakov V, Novakova O, Churnosova M, Sorokina I, Aristova I, Polonikov A, et al.
Life (Basel)
. 2023 Feb;
13(2).
PMID: 36836762
This study was conducted to examine the associations between genome-wide association studies (GWAS)-important single nucleotide polymorphisms (SNPs) and knee osteoarthritis (KOA) among Europeans of Russia. The present replicative study ("patient-control"...
6.
Hreusova M, Brabec V, Novakova O
Int J Mol Sci
. 2021 Oct;
22(19).
PMID: 34639179
DNA-dependent DNA and RNA polymerases are important modulators of biological functions such as replication, transcription, recombination, or repair. In this work performed in cell-free media, we studied the ability of...
7.
Shi H, Kasparkova J, Soulie C, Clarkson G, Imberti C, Novakova O, et al.
Chemistry
. 2021 May;
27(41):10711-10716.
PMID: 34046954
Photoactivatable agents offer the prospect of highly selective cancer therapy with low side effects and novel mechanisms of action that can combat current drug resistance. 1,8-Naphthalimides with their extended π...
8.
Tibenska V, Marvanova A, Elsnicova B, Hejnova L, Vebr P, Novotny J, et al.
J Appl Physiol (1985)
. 2020 Dec;
130(3):746-755.
PMID: 33332989
The infarct size-limiting effect elicited by cold acclimation (CA) is accompanied by increased mitochondrial resistance and unaltered β-adrenergic receptor (AR) signaling persisting for 2 wk at room temperature. As the...
9.
Hreusova M, Novakova O, Brabec V
Int J Mol Sci
. 2020 Oct;
21(20).
PMID: 33096927
Translesion synthesis (TLS) through DNA adducts of antitumor platinum complexes has been an interesting aspect of DNA synthesis in cells treated with these metal-based drugs because of its correlation to...
10.
Hoeschele J, Kasparkova J, Kostrhunova H, Novakova O, Pracharova J, Pineau P, et al.
J Biol Inorg Chem
. 2020 Aug;
25(6):913-924.
PMID: 32851480
The search for more effective platinum anticancer drugs has led to the design, synthesis, and preclinical testing of hundreds of new platinum complexes. This search resulted in the recognition and...