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Frantisek Kolar

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Articles 91
Citations 1166
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Recent Articles
1.
Jarabicova I, Horvath C, Hrdlicka J, Boros A, Olejnickova V, Zabrodska E, et al.
Basic Res Cardiol . 2025 Mar; PMID: 40088261
Since cell dying in heart failure (HF) may vary based on the aetiology, we examined the main forms of regulated necrosis, such as necroptosis and pyroptosis, in the hearts damaged...
2.
Benak D, Holzerova K, Kolar F, Chalupova M, Hlavackova M
Front Physiol . 2024 Oct; 15:1462014. PMID: 39469441
Fasting is a common dietary intervention known for its protective effects against metabolic and cardiovascular diseases. While its effects are mostly systemic, understanding tissue-specific changes in the heart is crucial...
3.
Gawrys O, Jichova S, Miklovic M, Huskova Z, Kikerlova S, Sadowski J, et al.
Hypertens Res . 2024 Sep; 47(11):3126-3146. PMID: 39245782
All anthracyclines, including doxorubicin (DOXO), the most common and still indispensable drug, exhibit cardiotoxicity with inherent risk of irreversible cardiomyopathy leading to heart failure with reduced ejection fraction (HFrEF). Current...
4.
Alanova P, Alan L, Opletalova B, Bohuslavova R, Abaffy P, Matejkova K, et al.
Acta Physiol (Oxf) . 2024 Jul; 240(9):e14202. PMID: 39016532
Aim: The transcriptional factor HIF-1α is recognized for its contribution to cardioprotection against acute ischemia/reperfusion injury. Adaptation to chronic hypoxia (CH) is known to stabilize HIF-1α and increase myocardial ischemic...
5.
Sedlar A, Vrbata D, Pokorna K, Holzerova K, cerveny J, Kockova O, et al.
J Med Chem . 2024 Jun; 67(11):9214-9226. PMID: 38829964
Pulmonary hypertension is a cardiovascular disease with a low survival rate. The protein galectin-3 (Gal-3) binding β-galactosides of cellular glycoproteins plays an important role in the onset and development of...
6.
Benak D, Holzerova K, Hrdlicka J, Kolar F, Olsen M, Karelson M, et al.
RNA Biol . 2024 Feb; 21(1):1-14. PMID: 38326277
Cardiac tolerance to ischaemia can be increased by dietary interventions such as fasting, which is associated with significant changes in myocardial gene expression. Among the possible mechanisms of how gene...
7.
Marvanova A, Kasik P, Elsnicova B, Tibenska V, Galatik F, Hornikova D, et al.
Sci Rep . 2023 Oct; 13(1):18287. PMID: 37880253
Moderate cold acclimation (MCA) is a non-invasive intervention mitigating effects of various pathological conditions including myocardial infarction. We aim to determine the shortest cardioprotective regimen of MCA and the response...
8.
Benak D, Kolar F, Zhang L, Devaux Y, Hlavackova M
Epigenetics . 2023 Jun; 18(1):2218771. PMID: 37331009
Epitranscriptomic modifications have recently emerged into the spotlight of researchers due to their vast regulatory effects on gene expression and thereby cellular physiology and pathophysiology. N,2'-O-dimethyladenosine (mAm) is one of...
9.
Ostadal B, Kolar F, Ostadalova I, Sedmera D, Olejnickova V, Hlavackova M, et al.
J Cardiovasc Dev Dis . 2023 May; 10(5). PMID: 37233172
The heart is capable of extensive adaptive growth in response to the demands of the body. When the heart is confronted with an increased workload over a prolonged period, it...
10.
Hrabalova P, Bohuslavova R, Matejkova K, Papousek F, Sedmera D, Abaffy P, et al.
Cardiovasc Diabetol . 2023 Apr; 22(1):88. PMID: 37072781
Background: An altered sympathetic nervous system is implicated in many cardiac pathologies, ranging from sudden infant death syndrome to common diseases of adulthood such as hypertension, myocardial ischemia, cardiac arrhythmias,...