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David Sedmera

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Articles 115
Citations 1782
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Recent Articles
1.
Sedmera D, Drobna Krejci E, Nanka O, Eckhardt A
Dev Biol . 2025 Feb; 521:28-36. PMID: 39933632
Investigating prenatal hypoxia is difficult in mammals, as there are confounding factors stemming from maternal adaptations and compensatory mechanisms. We have thus established an avian model of hypoxic incubation (starting...
2.
Sedmera D, Baldini A, van den Hoff M, Chaudhry B
J Cardiovasc Dev Dis . 2024 Dec; 11(12). PMID: 39728280
The International Cardiovascular Anatomy, Development, and Regeneration meeting was held from 18-20 September 2024, in Prague, Czech Republic, supported by the European Society of Cardiology's Working Group on Development, Anatomy,...
3.
Munoz-Martin N, Simon-Chica A, Diaz-Diaz C, Cadenas V, Temino S, Esteban I, et al.
Cardiovasc Res . 2024 Dec; PMID: 39691060
Aims: The Cardiac Conduction System (CCS) is progressively specified during development by interactions among a discrete number of Transcriptions Factors that ensure its proper patterning and the emergence of its...
4.
Sedmera D, Olejnickova V, Sankova B, Kolesova H, Bartos M, Kvasilova A, et al.
Front Cell Dev Biol . 2024 Oct; 12:1471751. PMID: 39435333
Left ventricular noncompaction cardiomyopathy is associated with heart failure, arrhythmia, and sudden cardiac death. The developmental mechanism underpinning noncompaction in the adult heart is still not fully understood, with lack...
5.
Boulgakoff L, Sturny R, Olejnickova V, Sedmera D, Kelly R, Miquerol L
Nat Cardiovasc Res . 2024 Sep; 3(9):1178. PMID: 39261682
No abstract available.
6.
Nanka O, Sedmera D, Rammelt S, Bartonicek J
Orthopadie (Heidelb) . 2024 Aug; 53(10):721-730. PMID: 39212710
The Achilles tendon (AT) is the strongest tendon of the human body. The knowledge of AT anatomy is a basic prerequisite for the successful treatment of acute and chronic lesions....
7.
Boulgakoff L, Sturny R, Olejnickova V, Sedmera D, Kelly R, Miquerol L
Nat Cardiovasc Res . 2024 Aug; 3(9):1140-1157. PMID: 39198628
Unlike adult mammals, newborn mice can regenerate a functional heart after myocardial infarction; however, the precise origin of the newly formed cardiomyocytes and whether the distal part of the conduction...
8.
Zabrodska E, Kvasilova A, Sedmera D, Olejnickova V
Am J Physiol Heart Circ Physiol . 2024 Jul; 327(3):H555-H564. PMID: 39028286
Atrioventricular (AV) accessory pathways (APs) provide additional electrical connections between the atria and ventricles, resulting in severe electrical disturbances. It is generally accepted that APs originate in the altered annulus...
9.
Chlupac J, Frank J, Sedmera D, Fabian O, Simunkova Z, Mrazova I, et al.
Biomedicines . 2024 Jun; 12(6). PMID: 38927542
Background: Autologous vein grafts are widely used for bypass procedures in cardiovascular surgery. However, these grafts are susceptible to failure due to vein graft disease. Our study aimed to evaluate...
10.
Gregorovicova M, Lashkarinia S, Yap C, Tomek V, Sedmera D
Adv Exp Med Biol . 2024 Jun; 1441:201-226. PMID: 38884713
A well-developed heart is essential for embryonic survival. There are constant interactions between cardiac tissue motion and blood flow, which determine the heart shape itself. Hemodynamic forces are a powerful...