Jan Silhavy
Overview
Explore the profile of Jan Silhavy including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
47
Citations
405
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Pecina P, Cunatova K, Kaplanova V, Puertas-Frias G, Silhavy J, Tauchmannova K, et al.
Commun Biol
. 2024 Sep;
7(1):1116.
PMID: 39261587
Metabolic syndrome is a growing concern in developed societies and due to its polygenic nature, the genetic component is only slowly being elucidated. Common mitochondrial DNA sequence variants have been...
2.
Nemeckova I, Eissazadeh S, Rathouska J, Silhavy J, Malinska H, Pravenec M, et al.
BMC Cardiovasc Disord
. 2024 Apr;
24(1):211.
PMID: 38627621
Background: C-reactive protein (CRP) is an acute inflammatory protein detected in obese patients with metabolic syndrome. Moreover, increased CRP levels have been linked with atherosclerotic disease, congestive heart failure, and...
3.
Silhavy J, Mlejnek P, Simakova M, Liska F, Malinska H, Markova I, et al.
Physiol Genomics
. 2023 Nov;
56(1):65-73.
PMID: 37955133
Recently, we have identified a recessive mutation, an abnormal coat appearance in the BXH6 strain, a member of the HXB/BXH set of recombinant inbred (RI) strains. The RI strains were...
4.
Huttl M, Markova I, Miklankova D, Zapletalova I, Kujal P, Silhavy J, et al.
Front Pharmacol
. 2023 Apr;
14:1117683.
PMID: 37077818
Low-grade chronic inflammation plays an important role in the pathogenesis of metabolic syndrome, type 2 diabetes and their complications. In this study, we investigated the effects of salsalate, a non-steroidal...
5.
Silhavy J, Mlejnek P, Simakova M, Markova I, Malinska H, Huttl M, et al.
PLoS One
. 2023 Apr;
18(4):e0283276.
PMID: 37053180
Thermogenesis in brown adipose tissue (BAT) uses intracellular triglycerides, circulating free fatty acids and glucose as the main substrates. The objective of the current study was to analyse the role...
6.
Silhavy J, Mlejnek P, Simakova M, Malinska H, Markova I, Huttl M, et al.
Metabolites
. 2023 Feb;
13(2).
PMID: 36837811
Recently, red beetroot has attracted attention as a health-promoting functional food. Studies have shown that beetroot administration can reduce blood pressure and ameliorate parameters of glucose and lipid metabolism; however,...
7.
Cizkova D, Zurmanova J, Gerykova L, Kouvelas A, Heles M, Elsnicova B, et al.
J Muscle Res Cell Motil
. 2023 Jan;
45(2):41-51.
PMID: 36690826
Nestin is a unique intermediate filament expressed for a short period in the developing heart. It was also documented in several cell types of the adult myocardium under pathological conditions...
8.
Malinska H, Huttl M, Markova I, Miklankova D, Hojna S, Papousek F, et al.
Biomedicines
. 2022 Sep;
10(9).
PMID: 36140169
Gliflozins (inhibitors of sodium-glucose cotransporter 2) show many beneficial actions beyond their antidiabetic effects. The underlying mechanisms of these additional protective effects are still not well understood, especially under non-diabetic...
9.
Senko A, Overall R, Silhavy J, Mlejnek P, Malinska H, Huttl M, et al.
PLoS Genet
. 2022 Apr;
18(4):e1009638.
PMID: 35377872
Neurogenesis in the adult hippocampus contributes to learning and memory in the healthy brain but is dysregulated in metabolic and neurodegenerative diseases. The molecular relationships between neural stem cell activity,...
10.
Lusk R, Hoffman P, Mahaffey S, Rosean S, Smith H, Silhavy J, et al.
Front Genet
. 2022 Apr;
13:821026.
PMID: 35368676
Post transcriptional modifications of RNA are powerful mechanisms by which eukaryotes expand their genetic diversity. For instance, researchers estimate that most transcripts in humans undergo alternative splicing and alternative polyadenylation....