Felix Lohmann
Overview
Explore the profile of Felix Lohmann including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
443
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0
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Recent Articles
1.
Namoto K, Baader C, Orsini V, Landshammer A, Breuer E, Dinh K, et al.
Cell Stem Cell
. 2024 Apr;
31(4):554-569.e17.
PMID: 38579685
The YAP/Hippo pathway is an organ growth and size regulation rheostat safeguarding multiple tissue stem cell compartments. LATS kinases phosphorylate and thereby inactivate YAP, thus representing a potential direct drug...
2.
Chen X, Pillay S, Lohmann F, Bieker J
J Biol Chem
. 2023 Nov;
299(12):105489.
PMID: 38000658
EKLF/KLF1 is an essential transcription factor that plays a global role in erythroid transcriptional activation. Regulation of KLF1 is of interest, as it displays a highly restricted expression pattern, limited...
3.
Sun T, Annunziato S, Bergling S, Sheng C, Orsini V, Forcella P, et al.
Cell Stem Cell
. 2021 Jun;
28(10):1822-1837.e10.
PMID: 34129813
AXIN2 and LGR5 mark intestinal stem cells (ISCs) that require WNT/β-Catenin signaling for constant homeostatic proliferation. In contrast, AXIN2/LGR5+ pericentral hepatocytes show low proliferation rates despite a WNT/β-Catenin activity gradient...
4.
Schutzius G, Kolter C, Bergling S, Tortelli F, Fuchs F, Renner S, et al.
Nat Chem Biol
. 2021 Jan;
17(3):280-290.
PMID: 33462494
Although most acute skin wounds heal rapidly, non-healing skin ulcers represent an increasing and substantial unmet medical need that urgently requires effective therapeutics. Keratinocytes resurface wounds to re-establish the epidermal...
5.
Ross N, Lohmann F, Carbonneau S, Fazal A, Weihofen W, Gleim S, et al.
Nat Chem Biol
. 2020 Mar;
16(4):479.
PMID: 32139909
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
6.
Sun T, Pikiolek M, Orsini V, Bergling S, Holwerda S, Morelli L, et al.
Cell Stem Cell
. 2019 Dec;
26(1):97-107.e6.
PMID: 31866224
The existence of specialized liver stem cell populations, including AXIN2 pericentral hepatocytes, that safeguard homeostasis and repair has been controversial. Here, using AXIN2 lineage tracing in BAC-transgenic mice, we confirm...
7.
Ross N, Lohmann F, Carbonneau S, Fazal A, Weihofen W, Gleim S, et al.
Nat Chem Biol
. 2019 Dec;
16(1):50-59.
PMID: 31819276
The post-genomic era has seen many advances in our understanding of cancer pathways, yet resistance and tumor heterogeneity necessitate multiple approaches to target even monogenic tumors. Here, we combine phenotypic...
8.
Mercado N, Schutzius G, Kolter C, Estoppey D, Bergling S, Roma G, et al.
Nat Commun
. 2019 Oct;
10(1):4676.
PMID: 31611556
Resident adult epithelial stem cells maintain tissue homeostasis by balancing self-renewal and differentiation. The stem cell potential of human epidermal keratinocytes is retained in vitro but lost over time suggesting...
9.
Bleu M, Gaulis S, Lopes R, Sprouffske K, Apfel V, Holwerda S, et al.
Nat Commun
. 2019 Aug;
10(1):3739.
PMID: 31431624
Transcription factor networks shape the gene expression programs responsible for normal cell identity and pathogenic state. Using Core Regulatory Circuitry analysis (CRC), we identify PAX8 as a candidate oncogene in...
10.
Lohmann F, Dangeti M, Soni S, Chen X, Planutis A, Baron M, et al.
Mol Cell Biol
. 2015 Aug;
35(21):3726-38.
PMID: 26303528
Understanding how transcriptional regulators are themselves controlled is important in attaining a complete picture of the intracellular effects that follow signaling cascades during early development and cell-restricted differentiation. We have...