Eveline Lescrinier
Overview
Explore the profile of Eveline Lescrinier including associated specialties, affiliations and a list of published articles.
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90
Citations
643
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Recent Articles
1.
Reynders S, Rihon J, Lescrinier E
J Chem Theory Comput
. 2025 Jan;
21(5):2798-2814.
PMID: 39869220
Synthetic nucleic acids, also defined as xenobiotic nucleic acids (XNAs), opened an avenue to address the limitations of nucleic acid therapeutics and the development of alternative carriers for genetic information...
2.
Li X, Groaz E, Herdewijn P, Lescrinier E
Chemistry
. 2024 Apr;
30(37):e202401254.
PMID: 38687344
An acyclic phosphonate-linked nucleic acid backbone (ZNA) demonstrated the capability to support duplex formation and propagate genetic information in vivo, unveiling its potential for evolution into a synthetic genetic system...
3.
Rihon J, Mattelaer C, Montalvao R, Froeyen M, Pinheiro V, Lescrinier E
Nucleic Acids Res
. 2024 Feb;
52(6):2836-2847.
PMID: 38412249
The field of synthetic nucleic acids with novel backbone structures [xenobiotic nucleic acids (XNAs)] has flourished due to the increased importance of XNA antisense oligonucleotides and aptamers in medicine, as...
4.
Schofield P, Taylor A, Rihon J, Pena Martinez C, Zinn S, Mattelaer C, et al.
Nucleic Acids Res
. 2023 Jul;
51(15):7736-7748.
PMID: 37439359
Nucleic acids not only form the basis of heredity, but are increasingly a source of novel nano-structures, -devices and drugs. This has spurred the development of chemically modified alternatives (xeno...
5.
Vriens E, De Ruysscher D, Weir A, Dekimpe S, Steurs G, Shemy A, et al.
Angew Chem Int Ed Engl
. 2023 May;
62(34):e202304476.
PMID: 37218580
Bacterial trans-acyltransferase polyketide synthases (trans-AT PKSs) are modular megaenzymes that employ unusual catalytic domains to assemble diverse bioactive natural products. One such PKS is responsible for the biosynthesis of the...
6.
Xu Y, Groaz E, Rihon J, Herdewijn P, Lescrinier E
Eur J Med Chem
. 2023 Apr;
255:115379.
PMID: 37120998
Molecular dynamics (MD) simulations provided insights into the favorable interactions between xylose nucleosides bearing a phosphonate moiety at their 3'-position and specific residues at the active site of the archetypal...
7.
Paulussen F, Kulkarni C, Stolz F, Lescrinier E, De Graeve S, Lambin S, et al.
Front Cell Dev Biol
. 2023 Jan;
10:1041930.
PMID: 36699012
The presence of sugar in the gut causes induction of SGLT1, the sodium/glucose cotransporter in intestinal epithelial cells (enterocytes), and this is accompanied by stimulation of sugar absorption. Sugar sensing...
8.
Staels F, de Keukeleere K, Kinnunen M, Keskitalo S, Lorenzetti F, Vanmeert M, et al.
Front Immunol
. 2022 Oct;
13:973543.
PMID: 36203612
NFKB1 haploinsufficiengcy was first described in 2015 in three families with common variable immunodeficiency (CVID), presenting heterogeneously with symptoms of increased infectious susceptibility, skin lesions, malignant lymphoproliferation and autoimmunity. The...
9.
Bardiot D, Vangeel L, Koukni M, Arzel P, Zwaagstra M, Lyoo H, et al.
Molecules
. 2022 Feb;
27(3).
PMID: 35164317
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, has led to a pandemic, that continues to be a huge public health burden. Despite the availability...
10.
Krentz D, Zenger K, Alberer M, Felten S, Bergmann M, Dorsch R, et al.
Viruses
. 2021 Nov;
13(11).
PMID: 34835034
Feline infectious peritonitis (FIP) caused by feline coronavirus (FCoV) is a common dis-ease in cats, fatal if untreated, and no effective treatment is currently legally available. The aim of this...