Estelle M N Laurent
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Explore the profile of Estelle M N Laurent including associated specialties, affiliations and a list of published articles.
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22
Citations
391
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Recent Articles
11.
Beganton B, Coyaud E, Laurent E, Mange A, Jacquemetton J, Le Romancer M, et al.
Cancers (Basel)
. 2020 Nov;
12(11).
PMID: 33187149
RAS proteins (KRAS, NRAS and HRAS) are frequently activated in different cancer types (e.g., non-small cell lung cancer, colorectal cancer, melanoma and bladder cancer). For many years, their activities were...
12.
Connaughton D, Dai R, Owen D, Marquez J, Mann N, Graham-Paquin A, et al.
Am J Hum Genet
. 2020 Sep;
107(4):727-742.
PMID: 32891193
Congenital anomalies of the kidney and urinary tract (CAKUT) constitute one of the most frequent birth defects and represent the most common cause of chronic kidney disease in the first...
13.
Astori A, Tingvall-Gustafsson J, Kuruvilla J, Coyaud E, Laurent E, Sunnerhagen M, et al.
J Immunol
. 2020 Aug;
205(5):1419-1432.
PMID: 32747500
Maturation of lymphoid cells is controlled by the action of stage and lineage-restricted transcription factors working in concert with the general transcription and chromatin remodeling machinery to regulate gene expression....
14.
Goncalves J, Sharma A, Coyaud E, Laurent E, Raught B, Pelletier L
J Cell Biol
. 2020 Jun;
219(7).
PMID: 32496561
Cilia and flagella are microtubule-based cellular projections with important sensory and motility functions. Their absence or malfunction is associated with a growing number of human diseases collectively referred to as...
15.
Cardon T, Franck J, Coyaud E, Laurent E, DAmato M, Maffia M, et al.
Nucleic Acids Res
. 2020 Apr;
48(14):7864-7882.
PMID: 32324228
It has been recently shown that many proteins are lacking from reference databases used in mass spectrometry analysis, due to their translation templated on alternative open reading frames. This questions...
16.
DCosta V, Coyaud E, Boddy K, Laurent E, St-Germain J, Li T, et al.
Nat Microbiol
. 2019 Oct;
4(12):2511-2522.
PMID: 31611645
Many bacterial pathogens express virulence proteins that are translocated into host cells (herein referred to as effectors), where they can interact with target proteins to manipulate host cell processes. These...
17.
Chan C, Le R, Burns K, Ahmed K, Coyaud E, Laurent E, et al.
Mol Cell Proteomics
. 2019 Sep;
18(11):2285-2297.
PMID: 31519766
The Golgi-specific Brefeldin-A resistance factor 1 (GBF1) is the only large GEF that regulates Arf activation at the Golgi and is actively recruited to membranes on an increase in Arf-GDP....
18.
Frendo-Cumbo S, Jaldin-Fincati J, Coyaud E, Laurent E, Townsend L, Tan J, et al.
J Biol Chem
. 2019 Sep;
294(44):16172-16185.
PMID: 31515271
Connections between deficient autophagy and insulin resistance have emerged, however, the mechanism through which reduced autophagy impairs insulin-signaling remains unknown. We examined mouse embryonic fibroblasts lacking (ATG16L1 KO mouse embryonic...
19.
Coyaud E, Ranadheera C, Cheng D, Goncalves J, Dyakov B, Laurent E, et al.
Mol Cell Proteomics
. 2018 Jul;
17(11):2242-2255.
PMID: 30037810
Zika virus (ZIKV) is a membrane enveloped Flavivirus with a positive strand RNA genome, transmitted by mosquitoes. The geographical range of ZIKV has dramatically expanded in recent decades resulting in...
20.
Kim B, Coyaud E, Laurent E, St-Germain J, Van de Laar E, Tsao M, et al.
Mol Cell Proteomics
. 2017 Aug;
16(10):1864-1888.
PMID: 28794006
Lung cancer is the leading cause of cancer mortality worldwide, with squamous cell carcinoma (SQCC) being the second most common form. SQCCs are thought to originate in bronchial basal cells...