Amira Klip
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Explore the profile of Amira Klip including associated specialties, affiliations and a list of published articles.
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140
Citations
5524
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Recent Articles
1.
Klip A, De Bock K, Bilan P, Richter E
Annu Rev Physiol
. 2024 Feb;
86:149-173.
PMID: 38345907
Glucose is the universal fuel of most mammalian cells, and it is largely replenished through dietary intake. Glucose availability to tissues is paramount for the maintenance of homeostatic energetics and,...
2.
Tokarz V, Mylvaganam S, Klip A
J Cell Sci
. 2023 Oct;
136(21).
PMID: 37815440
Skeletal muscle insulin resistance, a major contributor to type 2 diabetes, is linked to the consumption of saturated fats. This insulin resistance arises from failure of insulin-induced translocation of glucose...
3.
Antonescu C, Ishikura S, Bilan P, Klip A
Curr Protoc
. 2023 Jun;
3(6):e803.
PMID: 37367531
Elevated blood glucose following a meal is cleared by insulin-stimulated glucose entry into muscle and fat cells. The hormone increases the amount of the glucose transporter GLUT4 at the plasma...
4.
Moller L, Ali M, Davey J, Raun S, Andersen N, Long J, et al.
Proc Natl Acad Sci U S A
. 2023 Jun;
120(27):e2211041120.
PMID: 37364105
The molecular events governing skeletal muscle glucose uptake have pharmacological potential for managing insulin resistance in conditions such as obesity, diabetes, and cancer. With no current pharmacological treatments to target...
5.
Tokarz V, Pereira R, Jaldin-Fincati J, Mylvaganam S, Klip A
Mol Biol Cell
. 2023 Feb;
34(4):ar28.
PMID: 36735487
The lymphatic circulation regulates transfer of tissue fluid and immune cells toward the venous circulation. While obesity impairs lymphatic vessel function, the contribution of lymphatic endothelial cells (LEC) to metabolic...
6.
Tammineni E, Figueroa L, Manno C, Varma D, Kraeva N, Ibarra C, et al.
Elife
. 2023 Feb;
12.
PMID: 36724092
Calcium ion movements between cellular stores and the cytosol govern muscle contraction, the most energy-consuming function in mammals, which confers skeletal myofibers a pivotal role in glycemia regulation. Chronic myoplasmic...
7.
Frendo-Cumbo S, Li T, Ammendolia D, Coyaud E, Laurent E, Liu Y, et al.
iScience
. 2022 Dec;
25(12):105668.
PMID: 36505937
[This corrects the article DOI: 10.1016/j.isci.2022.105188.].
8.
Frendo-Cumbo S, Li T, Ammendolia D, Coyaud E, Laurent E, Liu Y, et al.
iScience
. 2022 Oct;
25(10):105188.
PMID: 36248734
Cell proliferation is dependent on growth factors insulin and IGF1. We sought to identify interactors of IRS1, the most proximal mediator of insulin/IGF1 signaling, that regulate cell proliferation. Using proximity-dependent...
9.
Boroumand P, Prescott D, Mukherjee T, Bilan P, Wong M, Shen J, et al.
Elife
. 2022 Sep;
11.
PMID: 36125130
During obesity and high fat-diet (HFD) feeding in mice, sustained low-grade inflammation includes not only increased pro-inflammatory macrophages in the expanding adipose tissue, but also bone marrow (BM) production of...
10.
Yazdani S, Bilan P, Jaldin-Fincati J, Pang J, Ceban F, Saran E, et al.
Mol Biol Cell
. 2022 Aug;
33(12):ar106.
PMID: 35921166
Endothelia determine blood-to-tissue solute delivery, yet glucose transit is poorly understood. To illuminate mechanisms, we tracked [H]-2-deoxyglucose (2-DG) in human adipose-tissue microvascular endothelial cells. 2-DG uptake was largely facilitated by...