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Sebastien Dussaud

Explore the profile of Sebastien Dussaud including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 568
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Recent Articles
1.
Lecoutre S, Rebiere C, Maqdasy S, Lambert M, Dussaud S, Abatan J, et al.
Nat Rev Endocrinol . 2025 Jan; PMID: 39757324
Adipose tissue demonstrates considerable plasticity and heterogeneity, enabling metabolic, cellular and structural adaptations to environmental signals. This adaptability is key for maintaining metabolic homeostasis. Impaired adipose tissue plasticity can lead...
2.
Murcy F, Borowczyk C, Gourion-Arsiquaud S, Torrino S, Ouahrouche N, Barouillet T, et al.
Nat Cardiovasc Res . 2024 Nov; 3(12):1454-1467. PMID: 39562782
Metabolic dysregulation, including perturbed glutamine-glutamate homeostasis, is common among patients with cardiovascular diseases, but the underlying mechanisms remain largely unknown. Using the human MESA cohort, here we show that plasma...
3.
Fima R, Dussaud S, Benbida C, Blanchet M, Lanthiez F, Poupel L, et al.
Nat Commun . 2024 Sep; 15(1):8341. PMID: 39333539
Hypercholesterolemia is a major risk factor for atherosclerosis and associated cardiovascular diseases. The liver plays a key role in the regulation of plasma cholesterol levels and hosts a large population...
4.
Gelineau A, Marcelin G, Ouhachi M, Dussaud S, Voland L, Manuel R, et al.
Nat Commun . 2024 Jun; 15(1):5413. PMID: 38926424
Diet composition impacts metabolic health and is now recognized to shape the immune system, especially in the intestinal tract. Nutritional imbalance and increased caloric intake are induced by high-fat diet...
5.
Lana J, Oliveira M, Silveira A, Yamada L, Costa K, da Silva S, et al.
Int J Obes (Lond) . 2024 Mar; 48(7):964-972. PMID: 38459259
Background/objectives: Proinflammatory cytokines are increased in obese adipose tissue, including inflammasome key masters. Conversely, IL-18 protects against obesity and metabolic dysfunction. We focused on the IL-18 effect in controlling adipose...
6.
Guilbaud E, Barouillet T, Ilie M, Borowczyk C, Ivanov S, Sarrazy V, et al.
Cell Stem Cell . 2023 Jun; 30(6):800-817.e9. PMID: 37267915
Cholesterol efflux pathways could be exploited in tumor biology to unravel cancer vulnerabilities. A mouse model of lung-tumor-bearing KRAS mutation with specific disruption of cholesterol efflux pathways in epithelial progenitor...
7.
Lopez-Herdoiza M, Bauche S, Wilmet B, Le Duigou C, Roussel D, Frah M, et al.
Front Cell Neurosci . 2023 May; 17:1155929. PMID: 37138765
The GGGGCC intronic repeat expansion within is the most common genetic cause of ALS and FTD. This mutation results in toxic gain of function through accumulation of expanded RNA foci...
8.
Gainullina A, Mogilenko D, Huang L, Todorov H, Narang V, Kim K, et al.
Cell Rep . 2023 Jan; 42(2):112046. PMID: 36708514
The diversity of mononuclear phagocyte (MNP) subpopulations across tissues is one of the key physiological characteristics of the immune system. Here, we focus on understanding the metabolic variability of MNPs...
9.
Merour E, Hmidan H, Marie C, Helou P, Lu H, Potel A, et al.
Elife . 2022 Oct; 11. PMID: 36214451
The differentiation of oligodendroglia from oligodendrocyte precursor cells (OPCs) to complex and extensive myelinating oligodendrocytes (OLs) is a multistep process that involves large-scale morphological changes with significant strain on the...
10.
Tran S, Baba I, Poupel L, Dussaud S, Moreau M, Gelineau A, et al.
Immunity . 2020 Jun; 53(3):627-640.e5. PMID: 32562600
Kupffer cells (KCs) are liver-resident macrophages that self-renew by proliferation in the adult independently from monocytes. However, how they are maintained during non-alcoholic steatohepatitis (NASH) remains ill defined. We found...