Claudia Jakubzick
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Explore the profile of Claudia Jakubzick including associated specialties, affiliations and a list of published articles.
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33
Citations
5614
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Recent Articles
1.
Gainullina A, Mogilenko D, Huang L, Todorov H, Narang V, Kim K, et al.
Cell Rep
. 2023 Jan;
42(2):112046.
PMID: 36708514
The diversity of mononuclear phagocyte (MNP) subpopulations across tissues is one of the key physiological characteristics of the immune system. Here, we focus on understanding the metabolic variability of MNPs...
2.
Ginhoux F, Mildner A, Gautier E, Schlitzer A, Jakubzick C, Varol C, et al.
Front Immunol
. 2021 Jan;
11:626725.
PMID: 33488633
No abstract available.
3.
Liu H, Jakubzick C, Osterburg A, Nelson R, Gupta N, McCormack F, et al.
Am J Respir Cell Mol Biol
. 2017 Jun;
57(4):393-402.
PMID: 28586276
Dendritic cells (DCs) are highly specialized immune cells that capture antigens and then migrate to lymphoid tissue and present antigen to T cells. This critical function of DCs is well...
4.
Frasch S, McNamee E, Kominsky D, Jedlicka P, Jakubzick C, Zemski Berry K, et al.
J Immunol
. 2016 Jul;
197(4):1425-34.
PMID: 27402702
Proinflammatory consequences have been described for lysophosphatidylcholine, a lipid product of cellular injury, signaling via the G protein-coupled receptor G2A on myeloid and lymphoid inflammatory cells. This prompted the hypothesis...
5.
Desch A, Gibbings S, Clambey E, Janssen W, Slansky J, Kedl R, et al.
Nat Commun
. 2014 Aug;
5:4674.
PMID: 25135627
Dendritic cells (DCs) are required for the induction of cytotoxic T cells (CTL). In most tissues, including the lung, the resident DCs fall into two types expressing the integrin markers...
6.
Guilliams M, Ginhoux F, Jakubzick C, Naik S, Onai N, Schraml B, et al.
Nat Rev Immunol
. 2014 Jul;
14(8):571-8.
PMID: 25033907
The mononuclear phagocyte system (MPS) has historically been categorized into monocytes, dendritic cells and macrophages on the basis of functional and phenotypical characteristics. However, considering that these characteristics are often...
7.
Jakubzick C, Gautier E, Gibbings S, Sojka D, Schlitzer A, Johnson T, et al.
Immunity
. 2013 Sep;
39(3):599-610.
PMID: 24012416
It is thought that monocytes rapidly differentiate to macrophages or dendritic cells (DCs) upon leaving blood. Here we have shown that Ly-6C⁺ monocytes constitutively trafficked into skin, lung, and lymph...
8.
Mingueneau M, Gray D, Cruse R, Bendall S, Spitzer M, Nolan G, et al.
Nat Immunol
. 2013 May;
14(6):619-32.
PMID: 23644507
The differentiation of αβT cells from thymic precursors is a complex process essential for adaptive immunity. Here we exploited the breadth of expression data sets from the Immunological Genome Project...
9.
Jojic V, Zuk O, Sun X, Best A, Knell J, Goldrath A, et al.
Nat Immunol
. 2013 Apr;
14(6):633-43.
PMID: 23624555
The differentiation of hematopoietic stem cells into cells of the immune system has been studied extensively in mammals, but the transcriptional circuitry that controls it is still only partially understood....
10.
Gautier E, Shay T, Miller J, Greter M, Jakubzick C, Ivanov S, et al.
Nat Immunol
. 2012 Oct;
13(11):1118-28.
PMID: 23023392
We assessed gene expression in tissue macrophages from various mouse organs. The diversity in gene expression among different populations of macrophages was considerable. Only a few hundred mRNA transcripts were...