Donna M Conlon
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Explore the profile of Donna M Conlon including associated specialties, affiliations and a list of published articles.
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16
Citations
286
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Recent Articles
1.
Conlon D, Kanakala S, Cherlin T, Ko Y, Vitali C, Gurunathan S, et al.
Genes (Basel)
. 2024 Aug;
15(8).
PMID: 39202457
Metabolic dysfunction-associated Fatty Liver Disease (MAFLD) has emerged as one of the leading cardiometabolic diseases. Friend of GATA2 (FOG2) is a transcriptional co-regulator that has been shown to regulate hepatic...
2.
Conlon D, Welty F, Reyes-Soffer G, Amengual J
Arterioscler Thromb Vasc Biol
. 2023 Jul;
43(9):1617-1625.
PMID: 37409532
Therapeutic approaches to reduce atherogenic lipid and lipoprotein levels remain the most effective and assessable strategies to prevent and treat cardiovascular disease. The discovery of novel research targets linked to...
3.
Schneider C, Hehl L, Creasy K, Vitali C, Vell M, Vujkovic M, et al.
Aliment Pharmacol Ther
. 2023 May;
58(2):238-249.
PMID: 37248657
Background: Genetic inactivation and pharmacologic inhibition of the microsomal triglyceride transfer protein (MTP; gene name MTTP) inhibits hepatic secretion of VLDL, thereby reducing serum lipids and apoB at the expense...
4.
Conlon D, Schneider C, Ko Y, Rodrigues A, Guo K, Hand N, et al.
J Clin Invest
. 2022 Feb;
132(6).
PMID: 35113816
Genetic variants at the SORT1 locus in humans, which cause increased SORT1 expression in the liver, are significantly associated with reduced plasma levels of LDL cholesterol and apolipoprotein B (apoB)....
5.
Quiroz-Figueroa K, Vitali C, Conlon D, Millar J, Tobias J, Bauer R, et al.
J Clin Invest
. 2021 Nov;
131(22).
PMID: 34779419
Genetic variants near the TRIB1 gene are highly significantly associated with plasma lipid traits and coronary artery disease. While TRIB1 is likely causal of these associations, the molecular mechanisms are...
6.
Schneider C, Schneider K, Conlon D, Park J, Vujkovic M, Zandvakili I, et al.
Med
. 2021 Jul;
2(7):851-863.e3.
PMID: 34258604
Background: A coding variant in (rs2642438; p.Ala165Thr) was recently associated with protection from cirrhosis in European individuals. However, its impact on overall and cause-specific mortality remained elusive. Methods: Using a...
7.
McCarron S, Bathon B, Conlon D, Abbey D, Rader D, Gawronski K, et al.
Hepatology
. 2021 Apr;
74(4):1825-1844.
PMID: 33901295
Background And Aims: NASH will soon become the leading cause of liver transplantation in the United States and is also associated with increased COVID-19 mortality. Currently, there are no Food...
8.
Conlon D
Curr Opin Lipidol
. 2019 Apr;
30(3):198-204.
PMID: 30946050
Purpose Of Review: Sortilin, encoded SORT1 gene at chromosome 1p13.3, is a multiligand receptor that traffics protein from the Golgi to the endosomes, secretory vesicles, and the cell surface. Genome-wide...
9.
Liu Y, Conlon D, Bi X, Slovik K, Shi J, Edelstein H, et al.
Cell Rep
. 2017 May;
19(7):1456-1466.
PMID: 28514664
Abetalipoproteinemia (ABL) is an inherited disorder of lipoprotein metabolism resulting from mutations in microsomal triglyceride transfer protein (MTTP). In addition to expression in the liver and intestine, MTTP is expressed...
10.
Cuchel M, Raper A, Conlon D, Pryma D, Freifelder R, Poria R, et al.
J Lipid Res
. 2017 Feb;
58(4):752-762.
PMID: 28167703
Reverse cholesterol transport (RCT) is thought to be an atheroprotective function of HDL, and macrophage-specific RCT in mice is inversely associated with atherosclerosis. We developed a novel method using H-cholesterol...