Donald Poirier
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Explore the profile of Donald Poirier including associated specialties, affiliations and a list of published articles.
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Articles
145
Citations
933
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Recent Articles
1.
Rusnac R, Garbuz O, Kravtsov V, Melnic E, Istrati D, Tsapkov V, et al.
Molecules
. 2025 Jan;
29(24.
PMID: 39770091
Ten coordination compounds, [Cu(L)Cl] (), [Cu(L)NO] (), [Cu(L)Cl] (C3), [Cu(L)NO] (), [Cu(L)Cl] (), [Cu(L)NO] (), [Cu(L)NO] (), [Cu(L)Cl] (), [Cu(L)Cl] (), and [Cu(L)NO] (), containing pyridine derivatives of -methoxyphenyl-thiosemicarbazones were...
2.
Poirier D
Steroids
. 2024 Nov;
213:109529.
PMID: 39532224
The family of 17β-hydroxysteroid dehydrogenases (17β-HSDs) occupies a prominent place due to its number of isoforms, which carry out a bidirectional transformation (reduction of a steroid carbonyl to alcohol and...
3.
Carleton N, Lee S, Li R, Zou J, Brown D, Hooda J, et al.
bioRxiv
. 2024 Nov;
PMID: 39484485
Translational Summary: We uncover the unique underpinnings establishing how the systemic host environment contributes to the aged breast tumor microenvironment, characterized by high local estradiol and chronic inflammation with immune...
4.
Sanceau J, Maltais R, Zhou M, Lin S, Poirier D
J Steroid Biochem Mol Biol
. 2024 May;
242:106544.
PMID: 38754521
Sex steroid hormones such as estrogen estradiol (E2) and androgen dihydrotestosterone (DHT) are involved in the development of hormone-dependent cancers. Blockade of 17β-hydroxysteroid dehydrogenase type 7 (17β-HSD7), a member of...
5.
Kariminezhad Z, Rahimi M, Fernandes J, Maltais R, Sanceau J, Poirier D, et al.
Antioxidants (Basel)
. 2024 Apr;
13(4).
PMID: 38671833
In osteoarthritis (OA), oxidative stress plays a crucial role in maintaining and sustaining cartilage degradation. Current OA management requires a combination of pharmaceutical and non-pharmacological strategies, including intraarticular injections of...
6.
Fortin N, Henaut M, Goyette N, Maltais R, Sanceau J, Marette A, et al.
J Med Virol
. 2024 Feb;
96(3):e29484.
PMID: 38402600
Antiviral therapy based on neuraminidase (oseltamivir) or polymerase (baloxavir marboxil) inhibitors plays an important role in the management of influenza infections. However, the emergence of drug resistance and the uncontrolled...
7.
Burguin A, Roy J, Ouellette G, Maltais R, Bherer J, Diorio C, et al.
J Clin Med
. 2023 Jul;
12(13).
PMID: 37445276
Breast cancer (BC) is a heterogenous disease classified into four molecular subtypes (Luminal A, Luminal B, HER2 and triple-negative (TNBC)) depending on the expression of the estrogen receptor (ER), the...
8.
Poirier D, Roy J, Maltais R, Weidmann C, Audet-Walsh E
Cancers (Basel)
. 2023 Jun;
15(11).
PMID: 37296995
The aminosteroid derivative RM-581 blocks with high potency the growth of androgen-dependent (AR) prostate cancer VCaP, 22Rv1, and LAPC-4 cells. Notably, RM-581 demonstrated superior antiproliferative activity in LAPC-4 cells compared...
9.
Maltais R, Sanceau J, Poirier D, Marette A
J Org Chem
. 2023 May;
88(11):7088-7095.
PMID: 37172290
We report a gram-scale total synthesis of protectin DX (PDX) following a convergent synthetic route (24 steps) from l-malic acid. This novel synthetic strategy is based on the assembly of...
10.
Poirier D
Molecules
. 2023 Apr;
28(8).
PMID: 37110733
Steroid hormones play a crucial role in several aspects of human life, and steroidogenesis is the process by which hormones are produced from cholesterol using several enzymes that work in...