Donald Poirier
Overview
Explore the profile of Donald Poirier including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
145
Citations
933
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Ngueta A, Roy J, Maltais R, Poirier D
Molecules
. 2023 Jan;
28(2).
PMID: 36677690
Estradiol (E2) plays an important role in the progression of diseases such as breast cancer and endometriosis. Inhibition of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1), the enzyme that catalyzes the last...
12.
Mansour M, Blanchette S, Pelletier M, Poirier D, Tchernof A
Clin Endocrinol (Oxf)
. 2022 Oct;
98(2):229-237.
PMID: 36267004
Context: 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) may be involved in the local modulation of estradiol (E2) availability in adipose tissues. Objective: To assess the conversion of E2 into estrone (E1)...
13.
Poirier D, Maltais R, Rousseau J, Roy J, Phoenix S, Cortes-Benitez F, et al.
Bioorg Chem
. 2022 Sep;
129:106145.
PMID: 36174444
Prostate cancer is the most common cancer among men and the development of new therapeutic agents is needed for its treatment and/or diagnosis. 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) is involved...
14.
Ngueta A, Roy J, Poirier D
Steroids
. 2022 Jun;
186:109064.
PMID: 35714784
Cancer remains one of the leading causes of death, worldwide. In addition, the lack of efficacy and selectivity of chemotherapeutic agents for cancer cells is a challenge that needs to...
15.
Poirier D, Nyachieo A, Romano A, Roy J, Maltais R, Chai D, et al.
J Steroid Biochem Mol Biol
. 2022 Jun;
222:106136.
PMID: 35691460
Endometriosis is a gynecological disorder affecting about 10% of women and can lead to invalidating painful symptoms and infertility. Since there is no current definitive cure for this disease, new...
16.
Sanceau J, Belanger P, Maltais R, Poirier D
Curr Org Synth
. 2022 Apr;
19(7):838-845.
PMID: 35473530
Aims And Objective: The syntheses of glucuronide metabolites of phenolic xenoestrogens triclosan and 2-phenylphenol, namely triclosan-O-glucuronide (TCS-G; 1), and 2-phenylphenol-Oglucuronide (OPP-G; 2), were achieved for use as analytical standards. Methods:...
17.
Maltais R, Roy J, Perreault M, Sato S, Levesque J, Poirier D
Int J Mol Sci
. 2021 Oct;
22(20).
PMID: 34681843
Aminosteroid derivative RM-581 was previously identified as an endoplasmic-reticulum (ER) stress inducer with potent in vitro and in vivo anticancer activities. We report its evaluation in androgen-independent prostate cancer (PC-3)...
18.
Theriault J, Poirier D, Lin S
J Steroid Biochem Mol Biol
. 2021 Aug;
214:105963.
PMID: 34400276
Human 17β-hydroxysteroid dehydrogenase type 7 (17β-HSD7), a special multifunctional enzyme, activates the estrogen estrone while inactivating the potent androgen dihydrotestosterone. Thus, this enzyme has become an ideal target for hormone-dependent...
19.
Maltais R, Roy J, Poirier D
ACS Med Chem Lett
. 2021 May;
12(5):822-826.
PMID: 34055232
RM-581 is an aminosteroid derivative comprised of a steroid core and a quinoline side chain showing potent cytotoxic activity on several types of cancer cells but for which the mechanism...
20.
Lesperance M, Roy J, Ngueta A, Maltais R, Poirier D
Steroids
. 2021 May;
172:108856.
PMID: 33945801
17β-Hydroxysteroid dehydrogenase type 1 (17β-HSD1) and steroid sulfatase (STS) are involved in the synthesis of the most potent estrogen in the human body, estradiol (E2). These enzymes are known to...