David V Hansen
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Explore the profile of David V Hansen including associated specialties, affiliations and a list of published articles.
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36
Citations
4904
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Recent Articles
21.
Visel A, Taher L, Girgis H, May D, Golonzhka O, Hoch R, et al.
Cell
. 2013 Feb;
152(4):895-908.
PMID: 23375746
The mammalian telencephalon plays critical roles in cognition, motor function, and emotion. Though many of the genes required for its development have been identified, the distant-acting regulatory sequences orchestrating their...
22.
Lui J, Hansen D, Kriegstein A
Cell
. 2011 Jul;
146(1):18-36.
PMID: 21729779
The size and surface area of the mammalian brain are thought to be critical determinants of intellectual ability. Recent studies show that development of the gyrated human neocortex involves a...
23.
Hansen D, Rubenstein J, Kriegstein A
Neuron
. 2011 May;
70(4):645-60.
PMID: 21609822
The human cerebral cortex is an immensely complex structure that subserves critical functions that can be disrupted in developmental and degenerative disorders. Recent innovations in cellular reprogramming and differentiation techniques...
24.
Hansen D, Lui J, Parker P, Kriegstein A
Nature
. 2010 Feb;
464(7288):554-561.
PMID: 20154730
Neurons in the developing rodent cortex are generated from radial glial cells that function as neural stem cells. These epithelial cells line the cerebral ventricles and generate intermediate progenitor cells...
25.
Tang W, Wu J, Guo Y, Hansen D, Perry J, Freel C, et al.
Mol Biol Cell
. 2008 Jun;
19(8):3536-43.
PMID: 18550795
The transition of oocytes from meiosis I (MI) to meiosis II (MII) requires partial cyclin B degradation to allow MI exit without S phase entry. Rapid reaccumulation of cyclin B...
26.
Wu J, Hansen D, Guo Y, Wang M, Tang W, Freel C, et al.
Proc Natl Acad Sci U S A
. 2007 Sep;
104(42):16564-9.
PMID: 17881560
Before fertilization, vertebrate eggs are arrested in meiosis II by cytostatic factor (CSF), which holds the anaphase-promoting complex (APC) in an inactive state. It was recently reported that Mos, an...
27.
Tung J, Padmanabhan K, Hansen D, Richter J, Jackson P
Cell Cycle
. 2007 Mar;
6(6):725-31.
PMID: 17361107
Cytostatic factor (CSF) arrests unfertilized vertebrate eggs in metaphase of meiosis II by inhibiting the anaphase-promoting complex/cyclosome (APC/C) from mediating cyclin destruction. The APC/C inhibitor Emi2/XErp1 satisfies a number of...
28.
Hansen D, Pomerening J, Summers M, Miller J, Ferrell Jr J, Jackson P
Cell Cycle
. 2007 Mar;
6(6):732-8.
PMID: 17361104
Vertebrate eggs arrest at metaphase of meiosis II due to an activity known as cytostatic factor (CSF). CSF antagonizes the ubiquitin ligase activity of the anaphase-promoting complex/cyclosome (APC/C), preventing cyclin...
29.
Madgwick S, Hansen D, Levasseur M, Jackson P, Jones K
J Cell Biol
. 2006 Sep;
174(6):791-801.
PMID: 16966421
During interkinesis, a metaphase II (MetII) spindle is built immediately after the completion of meiosis I. Oocytes then remain MetII arrested until fertilization. In mouse, we find that early mitotic...
30.
Miller J, Summers M, Hansen D, Nachury M, Lehman N, Loktev A, et al.
Genes Dev
. 2006 Aug;
20(17):2410-20.
PMID: 16921029
The periodic destruction of mitotic cyclins is triggered by the activation of the anaphase-promoting complex/cyclosome (APC/C) in mitosis. Although the ability of the APC/C to recognize destruction box (D-box) substrates...