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David Sedmera

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Articles 115
Citations 1782
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Recent Articles
11.
Hojna S, Malinska H, Huttl M, Vanourkova Z, Markova I, Miklankova D, et al.
Biomed Pharmacother . 2024 Apr; 174:116520. PMID: 38581924
A combination of liver and heart dysfunction worsens the prognosis of human survival. The aim of this study was to investigate whether empagliflozin (a sodium-glucose transporter-2 inhibitor) has beneficial effects...
12.
Kolesova H, Hrabalova P, Bohuslavova R, Abaffy P, Fabriciova V, Sedmera D, et al.
Front Endocrinol (Lausanne) . 2024 Mar; 15:1344074. PMID: 38505753
Introduction: Maternal diabetes is a recognized risk factor for both short-term and long-term complications in offspring. Beyond the direct teratogenicity of maternal diabetes, the intrauterine environment can influence the offspring's...
13.
Sedmera D, Kvasilova A, Eckhardt A, Kacer P, Penicka M, Kocka M, et al.
Histochem Cell Biol . 2024 Feb; 161(5):367-379. PMID: 38347221
Valvular heart disease leads to ventricular pressure and/or volume overload. Pressure overload leads to fibrosis, which might regress with its resolution, but the limits and details of this reverse remodeling...
14.
Miklovic M, Gawrys O, Honetschlagerova Z, Kala P, Huskova Z, Kikerlova S, et al.
Hypertens Res . 2024 Feb; 47(10):2718-2730. PMID: 38302774
Renal nerves play a critical role in cardiorenal interactions. Renal denervation (RDN) improved survival in some experimental heart failure (HF) models. It is not known whether these favorable effects are...
15.
Jensen B, Chang Y, Bamforth S, Mohun T, Sedmera D, Bartos M, et al.
J Anat . 2024 Jan; 244(6):1040-1053. PMID: 38284175
That the highly trabeculated ventricular walls of the developing embryos transform to the arrangement during the fetal stages, when the mural architecture is dominated by the thickness of the compact...
16.
Farkasova Iannaccone S, Sedmera D, Ginelliova A, Bohus P, Mistrikova L, Farkas D
J Cardiovasc Dev Dis . 2023 Sep; 10(9). PMID: 37754799
Cor triatriatum is a very rare cardiac malformation characterized by the presence of an abnormal interatrial membrane separating either the left or right atrial chamber into two compartments. It can...
17.
Ostadal B, Kolar F, Ostadalova I, Sedmera D, Olejnickova V, Hlavackova M, et al.
J Cardiovasc Dev Dis . 2023 May; 10(5). PMID: 37233172
The heart is capable of extensive adaptive growth in response to the demands of the body. When the heart is confronted with an increased workload over a prolonged period, it...
18.
Hrabalova P, Bohuslavova R, Matejkova K, Papousek F, Sedmera D, Abaffy P, et al.
Cardiovasc Diabetol . 2023 Apr; 22(1):88. PMID: 37072781
Background: An altered sympathetic nervous system is implicated in many cardiac pathologies, ranging from sudden infant death syndrome to common diseases of adulthood such as hypertension, myocardial ischemia, cardiac arrhythmias,...
19.
Olejnickova V, Hamor P, Janacek J, Bartos M, Zabrodska E, Sankova B, et al.
Dev Dyn . 2022 Nov; 253(1):78-90. PMID: 36400745
Background: The ventricular trabeculae play a role, among others, in the impulse spreading in ectothermic hearts. Despite the morphological similarity with the early developing hearts of endotherms, this trabecular function...
20.
Gregorovicova M, Bartos M, Jensen B, Janacek J, Minne B, Moravec J, et al.
Ecol Evol . 2022 Nov; 12(11):e9476. PMID: 36381397
The group Anguimorpha represents one of the most unified squamate clades in terms of body plan, ecomorphology, ecophysiology and evolution. On the other hand, the anguimorphs vary between different habitats...