David Sabatino
Overview
Explore the profile of David Sabatino including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
35
Citations
194
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Patel P, Rana N, Patel M, Kozuch S, Sabatino D
ChemMedChem
. 2015 Dec;
11(3):252-69.
PMID: 26663095
Nucleoside- and nucleotide-based chemotherapeutics have been used to treat cancer for more than 50 years. However, their inherent cytotoxicities and the emergent resistance of tumors against treatment has inspired a...
22.
Kurian L, Silva T, Sabatino D
Bioorg Med Chem Lett
. 2014 Aug;
24(17):4176-80.
PMID: 25127870
Azapeptide ligands of the Insulin Receptor Tyrosine Kinase (IRTK) were developed by solid-phase submonomer azapeptide synthesis in sufficient isolated yields (36-55%) and purities >95% for structure-activity relationship studies. The azapeptides...
23.
Joseph S, Blackman B, Kelly M, Phillips M, Beaury M, Martinez I, et al.
J Pept Sci
. 2014 Jun;
20(9):736-45.
PMID: 24931620
The solid-phase synthesis, structural characterization, and biological evaluation of a small library of cancer-targeting peptides have been determined in HepG2 hepatoblastoma cells. These peptides are based on the highly specific...
24.
Patel P, Patel H, Borland E, Gorun S, Sabatino D
Chem Commun (Camb)
. 2014 Mar;
50(48):6309-11.
PMID: 24663147
The first representative of functionalized fluoroalkyl phthalocyanines, F48H7(COOH)PcZn, is reported. The complex generates (1)O2 affording long-lasting photooxidation of an external substrate without self-decomposition. The carboxylic group couples with an antisense...
25.
Maina A, Blackman B, Parronchi C, Morozko E, Bender M, Blake A, et al.
Bioorg Med Chem Lett
. 2013 Aug;
23(19):5270-4.
PMID: 23988358
Linear, branch and hyperbranch siRNAs were effectively prepared for down-regulating GRP78 expression and inducing cell death in HepG2 liver cancer cells. Branch and hyperbranch GRP78 siRNAs were synthesized by automated...
26.
Patel P, Hanawa E, Yadav R, Samuni U, Marzabadi C, Sabatino D
Bioorg Med Chem Lett
. 2013 Aug;
23(18):5086-90.
PMID: 23932791
The synthesis and characterization of a new class of DNA binding molecule exhibiting potent and selective anti-leukemic activity is described. The synthesis of an aminoacyl nucleolipid was developed from an...
27.
Jamieson A, Boutard N, Sabatino D, Lubell W
Chem Biol Drug Des
. 2012 Dec;
81(1):148-65.
PMID: 23253136
Peptide-based therapeutics have grown in importance over the last few decades. Furthermore, peptides have been extensively used as lead compounds in the drug discovery process to investigate the nature of...
28.
Proulx C, Sabatino D, Hopewell R, Spiegel J, Garcia Ramos Y, Lubell W
Future Med Chem
. 2011 Aug;
3(9):1139-64.
PMID: 21806378
Azapeptides are peptide analogs in which one or more of the amino residues is replaced by a semicarbazide. This substitution of a nitrogen for the α-carbon center results in conformational...
29.
Sabatino D, Proulx C, Pohankova P, Ong H, Lubell W
J Am Chem Soc
. 2011 Jun;
133(32):12493-506.
PMID: 21692501
The cluster of differentiation 36 (CD36) class B scavenger receptor binds a variety of biologically endogenous ligands in addition to synthetic peptides (i.e., growth hormone-releasing peptides, GHRPs), which modulate biological...
30.
Bourguet C, Proulx C, Klocek S, Sabatino D, Lubell W
J Pept Sci
. 2010 May;
16(6):284-96.
PMID: 20474040
Aza-peptides have been used as tools for studying SARs in programs aimed at drug discovery and chemical biology. Protected aza-dipeptides were synthesized by a solution-phase submonomer approach featuring alkylation of...