Stephen D Kozuch
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Explore the profile of Stephen D Kozuch including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
62
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Recent Articles
1.
Sarkar B, Siddiqui Z, Nguyen P, Dube N, Fu W, Park S, et al.
ACS Biomater Sci Eng
. 2021 Jan;
5(9):4657-4670.
PMID: 33448838
Self-assembled peptide nanofibers can form biomimetic hydrogels at physiological pH and ionic strength through noncovalent and reversible interactions. Inspired by natural antimicrobial peptides, we designed a class of cationic amphiphilic...
2.
Cultrara C, Kozuch S, Ramasundaram P, Heller C, Shah S, Beck A, et al.
BMC Cancer
. 2018 Dec;
18(1):1263.
PMID: 30563499
Background: Glucose regulated protein 78 (GRP78) is a resident chaperone of the endoplasmic reticulum and a master regulator of the unfolded protein response under physiological and pathological cell stress conditions....
3.
Cultrara C, Shah S, Kozuch S, Patel M, Sabatino D
Chem Biol Drug Des
. 2018 Nov;
93(6):999-1010.
PMID: 30480355
New methods for the synthesis of higher-order siRNA motifs and their bioconjugates have recently gained widespread attention in the development of new and improved gene therapeutics. Our efforts aim to...
4.
Kozuch S, Cultrara C, Beck A, Heller C, Shah S, Patel M, et al.
ACS Omega
. 2018 Nov;
3(10):12975-12984.
PMID: 30411024
The integration of therapy and diagnostics, termed "theranostics", has recently gained widespread utility in the development of new and improved therapeutics that effectively diagnose and treat diseases, such as cancer....
5.
Shah S, Cultrara C, Kozuch S, Patel M, Ramos J, Samuni U, et al.
Bioconjug Chem
. 2018 Sep;
29(11):3638-3648.
PMID: 30235926
The emerging field of RNAi nanotechnology has led to rapid advances in the applications of siRNAs in chemical biology, medicinal chemistry, and biotechnology. In our RNAi approach, bioconjugation of linear,...
6.
Patel M, Kozuch S, Cultrara C, Yadav R, Huang S, Samuni U, et al.
Nano Lett
. 2016 Sep;
16(10):6099-6108.
PMID: 27669096
The emerging field of RNA nanotechnology has been used to design well-programmed, self-assembled nanostructures for applications in chemistry, biology, and medicine. At the forefront of its utility in cancer is...
7.
Patel P, Rana N, Patel M, Kozuch S, Sabatino D
ChemMedChem
. 2015 Dec;
11(3):252-69.
PMID: 26663095
Nucleoside- and nucleotide-based chemotherapeutics have been used to treat cancer for more than 50 years. However, their inherent cytotoxicities and the emergent resistance of tumors against treatment has inspired a...
8.
Twomey E, Cordasco D, Kozuch S, Wei Y
PLoS One
. 2014 Jan;
8(12):e83421.
PMID: 24391764
Protein conformational changes are commonly associated with the formation of protein complexes. The non-catalytic death effector domains (DEDs) mediate protein-protein interactions in a variety of cellular processes, including apoptosis, proliferation...