David E Lefebvre
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Explore the profile of David E Lefebvre including associated specialties, affiliations and a list of published articles.
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17
Citations
289
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Recent Articles
1.
La Vieille S, Lefebvre D, Khalid A, Decan M, Godefroy S
Nutr Rev
. 2018 Nov;
77(2):96-106.
PMID: 30380124
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme deficiency in the world and renders those affected susceptible to potentially severe oxidative hemolysis. Although the resulting hemolysis is most often...
2.
Bondy G, Coady L, Ross N, Caldwell D, Gannon A, Kwong K, et al.
Mycotoxin Res
. 2018 Jul;
34(4):241-255.
PMID: 29971579
The presence of the mycotoxin ochratoxin A (OTA) in cereal grains is due to the growth of toxigenic Penicillium mold on stored crops. Human exposure to OTA is higher in...
3.
Lefebvre D, Ross N, Kocmarek A, Cowell S, Dai S, Qiao C, et al.
Food Chem Toxicol
. 2017 Nov;
110:395-401.
PMID: 29107027
The chemical amaranth (AM) is permitted as a colouring agent in a variety of foods. Safety was established based on chronic rodent studies. AM and its metabolite naphthionic acid (NA)...
4.
Curran I, Liston V, Nunnikhoven A, Caldwell D, Scuby M, Pantazopoulos P, et al.
Toxicology
. 2016 Dec;
377:1-13.
PMID: 27932249
The brominated flame retardant TBECH is used as an additive to delay ignition and inhibit fires in construction materials and consumer goods. Trends in human exposure are not clear, although...
5.
Fine J, Bondy G, Coady L, Pearce B, Ross N, Tayabali A, et al.
Nanotoxicology
. 2016 Aug;
10(10):1422-1430.
PMID: 27534448
Humans could become exposed to carbon black nanoparticles (CBNPs) in consumer products or an occupational setting. In rodent models, acute respiratory, subcutaneous, and direct immune cell exposure to CBNPs has...
6.
Bondy G, Caldwell D, Aziz S, Coady L, Armstrong C, Curran I, et al.
Toxicol Pathol
. 2015 Feb;
43(5):715-29.
PMID: 25694087
Exposure to the mycotoxin ochratoxin A (OTA) causes nephropathy in domestic animals and rodents and renal tumors in rodents and poultry. Humans are exposed to OTA by consuming foods made...
7.
Bellmann S, Carlander D, Fasano A, Momcilovic D, Scimeca J, Waldman W, et al.
Wiley Interdiscip Rev Nanomed Nanobiotechnol
. 2015 Feb;
7(5):609-22.
PMID: 25641962
Many natural chemicals in food are in the nanometer size range, and the selective uptake of nutrients with nanoscale dimensions by the gastrointestinal (GI) tract is a normal physiological process....
8.
Lefebvre D, Venema K, Gombau L, Valerio Jr L, Raju J, Bondy G, et al.
Nanotoxicology
. 2014 Aug;
9(4):523-42.
PMID: 25119418
Engineered metal/mineral, lipid and biochemical macromolecule nanomaterials (NMs) have potential applications in food. Methodologies for the assessment of NM digestion and bioavailability in the gastrointestinal tract are nascent and require...
9.
Zhang Y, Nguyen K, Lefebvre D, Shwed P, Crosthwait J, Bondy G, et al.
J Nanopart Res
. 2014 Jun;
16:2440.
PMID: 24944520
The increasing use of zinc oxide nanoparticles (ZnO-NPs) has raised concerns about their potential hazards to human and environmental health. In this study, the characterization and cytotoxicity of two ZnO-NPs...
10.
Lefebvre D, Pearce B, Fine J, Chomyshyn E, Ross N, Halappanavar S, et al.
Toxicol Sci
. 2014 Jan;
138(2):322-32.
PMID: 24449417
Agglomerated carbon black nanoparticles (CBNPs) administered via respiratory or subcutaneous routes have been shown to promote allergic sensitization to coadministered ovalbumin (OVA) protein in rodents. In the present study, we...