Jason H Fine
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Explore the profile of Jason H Fine including associated specialties, affiliations and a list of published articles.
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188
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Recent Articles
1.
Tanaka M, Fine J, Kirkham C, Aguilar O, Belcheva A, Martin A, et al.
Cancer Res
. 2018 Apr;
78(13):3589-3603.
PMID: 29691253
Natural killer (NK) cells express receptors specific for MHC class I (MHC-I) molecules involved in "missing-self" recognition of cancer and virus-infected cells. Here we elucidate the role of MHC-I-independent NKR-P1B:Clr-b...
2.
Tayabali A, Zhang Y, Fine J, Caldwell D, Navarro M
Food Chem Toxicol
. 2018 Feb;
116(Pt A):32-41.
PMID: 29454867
Microbial-based cleaning products (MBCPs) contain bacteria and chemical constituents. They are used in consumer applications such as odor reduction, unclogging drains, and surface cleaning. To determine the capacity of a...
3.
Lefebvre D, Ross N, Kocmarek A, Cowell S, Dai S, Qiao C, et al.
Food Chem Toxicol
. 2017 Nov;
110:395-401.
PMID: 29107027
The chemical amaranth (AM) is permitted as a colouring agent in a variety of foods. Safety was established based on chronic rodent studies. AM and its metabolite naphthionic acid (NA)...
4.
Kirkham C, Aguilar O, Yu T, Tanaka M, Mesci A, Chu K, et al.
J Innate Immun
. 2017 Mar;
9(4):343-358.
PMID: 28288457
Natural killer (NK) cells are innate lymphocytes that aid in self-nonself discrimination by recognizing cells undergoing pathological alterations. The NKR-P1B inhibitory receptor recognizes Clr-b, a self-encoded marker of cell health...
5.
Fine J, Bondy G, Coady L, Pearce B, Ross N, Tayabali A, et al.
Nanotoxicology
. 2016 Aug;
10(10):1422-1430.
PMID: 27534448
Humans could become exposed to carbon black nanoparticles (CBNPs) in consumer products or an occupational setting. In rodent models, acute respiratory, subcutaneous, and direct immune cell exposure to CBNPs has...
6.
Chen P, Aguilar O, Rahim M, Allan D, Fine J, Kirkham C, et al.
J Immunol
. 2015 Feb;
194(6):2909-18.
PMID: 25681346
MHC-I-specific receptors play a vital role in NK cell-mediated "missing-self" recognition, which contributes to NK cell activation. In contrast, MHC-independent NK recognition mechanisms are less well characterized. In this study,...
7.
Lefebvre D, Pearce B, Fine J, Chomyshyn E, Ross N, Halappanavar S, et al.
Toxicol Sci
. 2014 Jan;
138(2):322-32.
PMID: 24449417
Agglomerated carbon black nanoparticles (CBNPs) administered via respiratory or subcutaneous routes have been shown to promote allergic sensitization to coadministered ovalbumin (OVA) protein in rodents. In the present study, we...
8.
Fine J, Chen P, Mesci A, Allan D, Gasser S, Raulet D, et al.
Cancer Res
. 2010 Sep;
70(18):7102-13.
PMID: 20823164
Natural killer (NK) cells can recognize and kill tumor cells lacking "self" markers, such as class I MHC, but the basis for this recognition is not completely understood. NKR-P1 receptors...
9.
Carlyle J, Mesci A, Fine J, Chen P, Belanger S, Tai L, et al.
Semin Immunol
. 2008 Jul;
20(6):321-30.
PMID: 18595730
The Ly49 and Nkrp1 loci encode structurally and functionally related cell surface proteins that positively or negatively regulate natural killer (NK) cell-mediated cytotoxicity and cytokine production. Yet despite their clear...
10.
Voigt S, Mesci A, Ettinger J, Fine J, Chen P, Chou W, et al.
Immunity
. 2007 Apr;
26(5):617-27.
PMID: 17462921
Cytomegaloviruses are known to encode several gene products that function to subvert MHC-dependent immune recognition. Here we characterize a rat cytomegalovirus (RCMV) C-type lectin-like (RCTL) gene product with homology to...