David Cobrinik
Overview
Explore the profile of David Cobrinik including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
50
Citations
1662
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Amacker A, Peng C, Jiang N, Sirivolu S, Higa N, Stachelek K, et al.
Int J Mol Sci
. 2024 Nov;
25(21).
PMID: 39519212
Recent advancements in aqueous humor (AH) cell-free DNA (cfDNA) genomics have opened new avenues for ex vivo molecular profiling of retinoblastoma (RB), the most common pediatric intraocular malignancy, where biopsy...
2.
Shayler D, Stachelek K, Cambier L, Lee S, Bai J, Reid M, et al.
bioRxiv
. 2024 Jun;
PMID: 38915659
Human cone photoreceptors differ from rods and serve as the retinoblastoma cell-of-origin, yet the developmental basis for their distinct behaviors is poorly understood. Here, we used deep full-length single-cell RNA-sequencing...
3.
4.
Bai J, Koos D, Stepanian K, Fouladian Z, Shayler D, Aparicio J, et al.
Dis Model Mech
. 2023 Oct;
16(11).
PMID: 37902188
Fluorescent reporter pluripotent stem cell-derived retinal organoids are powerful tools to investigate cell type-specific development and disease phenotypes. When combined with live imaging, they enable direct and repeated observation of...
5.
Aparicio J, Hopp H, Harutyunyan N, Stewart C, Cobrinik D, Borchert M
Ophthalmic Genet
. 2023 Oct;
45(1):1-15.
PMID: 37807874
Background: Optic nerve hypoplasia (ONH), the leading congenital cause of permanent blindness, is characterized by a retinal ganglion cell (RGC) deficit at birth. Multifactorial developmental events are hypothesized to underlie...
6.
Bai J, Koos D, Stepanian K, Fouladian Z, Shayler D, Aparicio J, et al.
bioRxiv
. 2023 Mar;
PMID: 36909527
Fluorescent reporter pluripotent stem cell (PSC) derived retinal organoids are powerful tools to investigate cell type-specific development and disease phenotypes. When combined with live imaging, they enable direct and repeated...
7.
Stachelek K, Harutyunyan N, Lee S, Beck A, Kim J, Xu L, et al.
Genes Chromosomes Cancer
. 2022 Dec;
62(5):275-289.
PMID: 36550020
Retinoblastomas form in response to biallelic RB1 mutations or MYCN amplification and progress to more aggressive and therapy-resistant phenotypes through accumulation of secondary genomic changes. Progression-related changes include recurrent somatic...
8.
Sanfilippo C, Javaheri M, Handler S, Berry J, Cobrinik D, Deardorff M, et al.
Ophthalmology
. 2022 Oct;
130(3):265-273.
PMID: 36270406
Purpose: To report the clinical and imaging findings of 4 patients with benign intraretinal tumors, 2 of which were associated with retinal pigment epithelium (RPE) hypertrophy. To our knowledge, this...
9.
Li H, Xu L, Weisenberger D, Li M, Zhou W, Peng C, et al.
Nat Commun
. 2022 Sep;
13(1):5523.
PMID: 36130950
Retinoblastoma (RB) is a cancer that forms in the developing retina of babies and toddlers. The goal of therapy is to cure the tumor, save the eye and maximize vision....
10.
Singh H, Shayler D, Fernandez G, Thornton M, Craft C, Grubbs B, et al.
Proc Natl Acad Sci U S A
. 2022 Jul;
119(28):e2200721119.
PMID: 35867756
Most retinoblastomas develop from maturing cone precursors in response to biallelic loss and are dependent on cone maturation-related signaling. Additionally, ∼2% lack mutations but have amplification (), N-Myc protein overexpression,...