David A F Loebel
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Explore the profile of David A F Loebel including associated specialties, affiliations and a list of published articles.
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30
Citations
951
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Recent Articles
1.
Fan X, Waardenberg A, Demuth M, Osteil P, Sun J, Loebel D, et al.
Mol Cell Biol
. 2020 Mar;
40(11).
PMID: 32179550
The extensive array of basic helix-loop-helix (bHLH) transcription factors and their combinations as dimers underpin the diversity of molecular function required for cell type specification during embryogenesis. The bHLH factor...
2.
Bildsoe H, Fan X, Wilkie E, Ashoti A, Jones V, Power M, et al.
Data Brief
. 2016 Oct;
9:372-375.
PMID: 27699189
This article contains data related to the research article entitled "Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance" by Bildsoe et al. (2016) [1]....
3.
Bildsoe H, Fan X, Wilkie E, Ashoti A, Jones V, Power M, et al.
Dev Biol
. 2016 Aug;
418(1):189-203.
PMID: 27546376
TWIST1, a basic helix-loop-helix transcription factor is essential for the development of cranial mesoderm and cranial neural crest-derived craniofacial structures. We have previously shown that, in the absence of TWIST1,...
4.
Zheng G, Zhang J, Zhao H, Wang H, Pang M, Qiao X, et al.
Am J Pathol
. 2016 May;
186(7):1847-1860.
PMID: 27182643
Loss of E-cadherin marks a defect in epithelial integrity and polarity during tissue injury and fibrosis. Whether loss of E-cadherin plays a causal role in fibrosis is uncertain. α3β1 Integrin...
5.
Tam P, Fossat N, Wilkie E, Loebel D, Ip C, Ramialison M
Curr Top Dev Biol
. 2016 Mar;
117:497-521.
PMID: 26969997
The embryonic head is the first major body part to be constructed during embryogenesis. The allocation and the assembly of the progenitor tissues, which start at gastrulation, are accompanied by...
6.
Loebel D, Plageman Jr T, Tang T, Jones V, Muccioli M, Tam P
Biol Open
. 2016 Jan;
5(2):130-9.
PMID: 26772200
Early development of the gut endoderm and its subsequent remodeling for the formation of organ buds are accompanied by changes to epithelial cell shape and polarity. Members of the Rho-related...
7.
Greenlees R, Mihelec M, Yousoof S, Speidel D, Wu S, Rinkwitz S, et al.
Hum Mol Genet
. 2015 Aug;
24(20):5789-804.
PMID: 26231217
Correct morphogenesis and differentiation are critical in development and maintenance of the lens, which is a classic model system for epithelial development and disease. Through germline genomic analyses in patients...
8.
Fossat N, Ip C, Jones V, Studdert J, Khoo P, Lewis S, et al.
Development
. 2015 May;
142(11):2069-79.
PMID: 25977363
Lhx1 encodes a LIM homeobox transcription factor that is expressed in the primitive streak, mesoderm and anterior mesendoderm of the mouse embryo. Using a conditional Lhx1 flox mutation and three...
9.
Kaufman-Francis K, Goh H, Kojima Y, Studdert J, Jones V, Power M, et al.
Philos Trans R Soc Lond B Biol Sci
. 2014 Oct;
369(1657).
PMID: 25349457
Mouse epiblast stem cells (EpiSCs) display temporal differences in the upregulation of Mixl1 expression during the initial steps of in vitro differentiation, which can be correlated with their propensity for...
10.
Fossat N, Tourle K, Radziewic T, Barratt K, Liebhold D, Studdert J, et al.
EMBO Rep
. 2014 Jun;
15(8):903-10.
PMID: 24916387
Cytidine (C) to Uridine (U) RNA editing is a post-transcriptional modification that is accomplished by the deaminase APOBEC1 and its partnership with the RNA-binding protein A1CF. We identify and characterise...