Joshua B Studdert
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Explore the profile of Joshua B Studdert including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
264
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Recent Articles
1.
Osteil P, Studdert J, Tam P
Methods Mol Biol
. 2022 Apr;
2490:269-279.
PMID: 35486252
Here we describe a method to engraft epiblast stem cells (EpiSC) into the epiblast of gastrulation-stage mouse embryo to test the lineage propensity acquired by the EpiSCs during in vitro...
2.
Studdert J, Bildsoe H, Masamsetti V, Tam P
Methods Mol Biol
. 2021 Dec;
2403:43-50.
PMID: 34913115
Craniofacial morphogenesis is underpinned by orchestrated growth and form-shaping activity of skeletal and soft tissues in the head and face. Disruptions during development can lead to dysmorphology of the skull,...
3.
Studdert J, Bildsoe H, Masamsetti V, Tam P
Methods Mol Biol
. 2021 Dec;
2403:33-42.
PMID: 34913114
Analysis of animal models allows a deeper understanding of craniofacial development in health and diseases of humans. Wholemount in situ hybridization (WISH) is an informative technique to visualize gene expression...
4.
Fossat N, Ip C, Jones V, Studdert J, Khoo P, Lewis S, et al.
Development
. 2015 May;
142(11):2069-79.
PMID: 25977363
Lhx1 encodes a LIM homeobox transcription factor that is expressed in the primitive streak, mesoderm and anterior mesendoderm of the mouse embryo. Using a conditional Lhx1 flox mutation and three...
5.
Kaufman-Francis K, Goh H, Kojima Y, Studdert J, Jones V, Power M, et al.
Philos Trans R Soc Lond B Biol Sci
. 2014 Oct;
369(1657).
PMID: 25349457
Mouse epiblast stem cells (EpiSCs) display temporal differences in the upregulation of Mixl1 expression during the initial steps of in vitro differentiation, which can be correlated with their propensity for...
6.
Fossat N, Tourle K, Radziewic T, Barratt K, Liebhold D, Studdert J, et al.
EMBO Rep
. 2014 Jun;
15(8):903-10.
PMID: 24916387
Cytidine (C) to Uridine (U) RNA editing is a post-transcriptional modification that is accomplished by the deaminase APOBEC1 and its partnership with the RNA-binding protein A1CF. We identify and characterise...
7.
Loebel D, Radziewic T, Power M, Studdert J, Tam P
Methods Mol Biol
. 2013 Dec;
1092:119-42.
PMID: 24318817
We are using knockdown of gene expression in mouse embryos by constitutive expression of small hairpin (sh)RNAs as a means of observing loss-of-function phenotypes more rapidly than gene targeting. Plasmid...
8.
Kojima Y, Kaufman-Francis K, Studdert J, Steiner K, Power M, Loebel D, et al.
Cell Stem Cell
. 2013 Oct;
14(1):107-20.
PMID: 24139757
Mouse epiblast stem cells (EpiSCs) can be derived from a wide range of developmental stages. To characterize and compare EpiSCs with different origins, we derived a series of EpiSC lines...
9.
Loebel D, Studdert J, Power M, Radziewic T, Jones V, Coultas L, et al.
Development
. 2011 Sep;
138(20):4511-22.
PMID: 21903671
Rhou encodes a Cdc42-related atypical Rho GTPase that influences actin organization in cultured cells. In mouse embryos at early-somite to early-organogenesis stages, Rhou is expressed in the columnar endoderm epithelium...