Nicolas Fossat
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Explore the profile of Nicolas Fossat including associated specialties, affiliations and a list of published articles.
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31
Citations
527
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Recent Articles
1.
Mullari M, Fossat N, Skotte N, Asenjo-Martinez A, Humphreys D, Bukh J, et al.
Nat Commun
. 2023 Jul;
14(1):4348.
PMID: 37468457
RNA-binding proteins (RBPs) are key players regulating RNA processing and are associated with disorders ranging from cancer to neurodegeneration. Here, we present a proteomics workflow for large-scale identification of RBPs...
2.
Sherwood A, Rivera-Rangel L, Ryberg L, Larsen H, Anker K, Costa R, et al.
Nature
. 2023 Jul;
619(7971):811-818.
PMID: 37407817
RNA viruses have evolved elaborate strategies to protect their genomes, including 5' capping. However, until now no RNA 5' cap has been identified for hepatitis C virus (HCV), which causes...
3.
Binderup A, Galli A, Fossat N, Fernandez-Antunez C, Mikkelsen L, Rivera-Rangel L, et al.
Virology
. 2023 Jun;
585:179-185.
PMID: 37356253
With no approved antiviral therapies, the continuous emergence and re-emergence of tick-borne encephalitis virus (TBEV) and yellow fever virus (YFV) is a rising concern. We performed head-to-head comparisons of the...
4.
Fossat N, Lundsgaard E, Costa R, Rivera-Rangel L, Nielsen L, Mikkelsen L, et al.
Cell Rep
. 2023 Mar;
42(4):112282.
PMID: 36961814
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has had a tremendous impact worldwide. Mapping virus-host interactions is critical to understand disease progression. MicroRNAs (miRNAs) are important RNA regulators,...
5.
Nim H, Dang L, Thiyagarajah H, Bakopoulos D, See M, Charitakis N, et al.
Genome Biol
. 2021 Dec;
22(1):335.
PMID: 34906219
Background: Congenital heart diseases are the major cause of death in newborns, but the genetic etiology of this developmental disorder is not fully known. The conventional approach to identify the...
6.
Fan X, Masamsetti V, Sun J, Engholm-Keller K, Osteil P, Studdert J, et al.
Elife
. 2021 Feb;
10.
PMID: 33554859
Protein interaction is critical molecular regulatory activity underlining cellular functions and precise cell fate choices. Using TWIST1 BioID-proximity-labeling and network propagation analyses, we discovered and characterized a TWIST-chromatin regulatory module...
7.
Kokkonos K, Fossat N, Nielsen L, Holm C, Hepkema W, Bukh J, et al.
Nucleic Acids Res
. 2020 May;
48(10):5555-5571.
PMID: 32374844
Host microRNA (miRNA) dependency is a hallmark of the human pathogen hepatitis C virus (HCV) and was also described for the related pestiviruses, which are important livestock pathogens. The liver-specific...
8.
Fan X, Waardenberg A, Demuth M, Osteil P, Sun J, Loebel D, et al.
Mol Cell Biol
. 2020 Mar;
40(11).
PMID: 32179550
The extensive array of basic helix-loop-helix (bHLH) transcription factors and their combinations as dimers underpin the diversity of molecular function required for cell type specification during embryogenesis. The bHLH factor...
9.
Humphreys D, Fossat N, Demuth M, Tam P, Ho J
Nucleic Acids Res
. 2019 Aug;
47(20):e123.
PMID: 31435647
Circular RNAs (circRNA) are a unique class of transcripts that can only be identified from sequence alignments spanning discordant junctions, commonly referred to as backsplice junctions (BSJ). Canonical splicing is...
10.
Osteil P, Studdert J, Goh H, Wilkie E, Fan X, Khoo P, et al.
Development
. 2019 Mar;
146(7).
PMID: 30890572
During embryogenesis, the stringent regulation of Wnt activity is crucial for the morphogenesis of the head and brain. The loss of function of the Wnt inhibitor Dkk1 results in elevated...