Curtis J Henrich
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Explore the profile of Curtis J Henrich including associated specialties, affiliations and a list of published articles.
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62
Citations
684
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Recent Articles
1.
Orfanoudaki M, Krumpe L, Shenoy S, Wilson J, Guszczynski T, Henrich C, et al.
J Biol Chem
. 2025 Feb;
301(3):108319.
PMID: 39956341
An anti-HIV screen of natural product extracts resulted in the discovery of a new antiviral protein through bioassay-guided fractionation of an aqueous extract of the ascidian Didemnum molle. The protein...
2.
Khong Q, Smith E, Wendt K, Dalilian M, Goncharova E, Brownell I, et al.
J Nat Prod
. 2024 Jul;
87(7):1826-1837.
PMID: 38995621
Merkel cell carcinoma (MCC) is a rare and aggressive cutaneous cancer. Two new prenylated indole 2,5-diketopiperazine alkaloids, brevianamides E1 () and E2 (), were isolated from a fungus. Both compounds...
3.
Orfanoudaki M, Akee R, Martinez-Fructuoso L, Wang D, Kelley J, Smith E, et al.
J Nat Prod
. 2024 Jan;
87(2):415-423.
PMID: 38291771
Pyrrole-containing natural products form a large group of structurally diverse compounds that occur in both terrestrial and marine organisms. In the present study the formation of trideuteromethylated artifacts of pyrrole-containing...
4.
Orfanoudaki M, Smith E, Hill N, Garman K, Brownell I, Copp B, et al.
Mar Drugs
. 2023 Sep;
21(9).
PMID: 37755087
A library of naturally occurring and semi-synthetic discorhabdins was assessed for their effects on Merkel cell carcinoma (MCC) cell viability. The set included five new natural products and semi-synthetic compounds...
5.
Takada K, Oku N, Peach M, Ransom T, Henrich C, Gustafson K
J Org Chem
. 2023 Jul;
88(15):10996-11002.
PMID: 37471139
Enigmazole B () and four new analogues, -enigmazole B (), dehydroenigmazole B (), enigmimide B (), and enigmimide A (), were isolated from the marine sponge . Their planar structures...
6.
Borhani S, Levine M, Krumpe L, Wilson J, Henrich C, OKeefe B, et al.
N Biotechnol
. 2023 Apr;
76:13-22.
PMID: 37054948
This study describes the cell-free biomanufacturing of a broad-spectrum antiviral protein, griffithsin (GRFT) such that it can be produced in microgram quantities with consistent purity and potency in less than...
7.
Munoz-Basagoiti J, Monteiro F, Krumpe L, Armario-Najera V, Shenoy S, Perez-Zsolt D, et al.
Proc Natl Acad Sci U S A
. 2023 Feb;
120(10):e2214561120.
PMID: 36853940
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive stranded RNA virus which has caused the recent deadly pandemic called COVID-19. The SARS-CoV-2 virion is coated with a...
8.
Borhani S, Levine M, Krumpe L, Wilson J, Henrich C, Oa Keefe B, et al.
bioRxiv
. 2023 Jan;
PMID: 36597541
This study describes the cell-free biomanufacturing of a broad-spectrum antiviral protein, griffithsin (GRFT) such that it can be produced with consistent purity and potency in less than 24 hours. We...
9.
Senadeera S, Wang D, Kim C, Smith E, Durrant D, Alexander P, et al.
J Nat Prod
. 2022 Jun;
85(6):1603-1616.
PMID: 35696348
Seven new peptaibols named tolypocladamides A-G have been isolated from an extract of the fungus , which inhibits the interaction between Raf and oncogenic Ras in a cell-based high-throughput screening...
10.
Kim C, Krumpe L, Smith E, Henrich C, Brownell I, Wendt K, et al.
Molecules
. 2021 Jul;
26(12).
PMID: 34208349
A new 11 amino acid linear peptide named roseabol A () and the known compound 13-oxo--9,10-epoxy-11()-octadecenoic acid () were isolated from the fungus . Combined NMR and MS analysis revealed...