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Cristian G Bologa

Explore the profile of Cristian G Bologa including associated specialties, affiliations and a list of published articles. Areas
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Articles 64
Citations 3116
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Recent Articles
1.
Simons P, Bondu V, Shevy L, Young S, Wandinger-Ness A, Bologa C, et al.
Front Cell Infect Microbiol . 2025 Mar; 15:1451293. PMID: 40041147
Introduction: Clinicians encounter significant challenges in quickly and accurately identifying the bacterial species responsible for patient bacteremia and in selecting appropriate antibiotics for timely treatment. This study introduces a novel...
2.
Kumar P, Moomtaheen F, Malec S, Yang J, Bologa C, Schneider K, et al.
IEEE J Biomed Health Inform . 2025 Mar; PP. PMID: 40030473
Accurate detection and prevalence estimation of behavioral health conditions, such as opioid use disorder (OUD), are crucial for identifying at-risk individuals, determining treatment needs, monitoring prevention and intervention efforts, and...
3.
Metzger V, Cannon D, Yang J, Mathias S, Bologa C, Waller A, et al.
PeerJ . 2024 Jul; 12:e17470. PMID: 38948230
TIN-X (Target Importance and Novelty eXplorer) is an interactive visualization tool for illuminating associations between diseases and potential drug targets and is publicly available at newdrugtargets.org. TIN-X uses natural language...
4.
Fara D, Oprea T, Prossnitz E, Bologa C, Edwards B, Sklar L
Drug Discov Today Technol . 2024 Apr; 3(4):377-385. PMID: 38620118
High-throughput screening (HTS) represents the dominant technique for the identification of new lead compounds in current drug discovery. It consists of physical screening (PS) of large libraries of chemicals against...
5.
Arzhan S, Roumelioti M, Litvinovich I, Bologa C, Unruh M
Clin J Am Soc Nephrol . 2023 Sep; 18(11):1396-1407. PMID: 37722368
Background: Hospital-acquired hypernatremia is highly prevalent, overlooked, and associated with unfavorable consequences. There are limited studies examining the outcomes and discharge dispositions of various levels of hospital-acquired hypernatremia in patients...
6.
Evangelista J, Clarke D, Xie Z, Marino G, Utti V, Jenkins S, et al.
Commun Med (Lond) . 2023 Jul; 3(1):98. PMID: 37460679
Background: Birth defects are functional and structural abnormalities that impact about 1 in 33 births in the United States. They have been attributed to genetic and other factors such as ...
7.
Kelleher K, Sheils T, Mathias S, Yang J, Metzger V, Siramshetty V, et al.
Nucleic Acids Res . 2023 Jan; 51(D1):D1405-D1416. PMID: 36624666
The Illuminating the Druggable Genome (IDG) project aims to improve our understanding of understudied proteins and our ability to study them in the context of disease biology by perturbing them...
8.
Avram S, Wilson T, Curpan R, Halip L, Borota A, Bora A, et al.
Nucleic Acids Res . 2022 Dec; 51(D1):D1276-D1287. PMID: 36484092
DrugCentral monitors new drug approvals and standardizes drug information. The current update contains 285 drugs (131 for human use). New additions include: (i) the integration of veterinary drugs (154 for...
9.
Arzhan S, Roumelioti M, Litvinovich I, Bologa C, Myers O, Unruh M
Kidney360 . 2022 Aug; 3(7):1144-1157. PMID: 35919520
Background: Hypernatremia is a frequently encountered electrolyte disorder in hospitalized patients. Controversies still exist over the relationship between hypernatremia and its outcomes in hospitalized patients. This study examines the relationship...
10.
Ackloo S, Al-Awar R, Amaro R, Arrowsmith C, Azevedo H, Batey R, et al.
Nat Rev Chem . 2022 Jul; 6(4):287-295. PMID: 35783295
One aspirational goal of computational chemistry is to predict potent and drug-like binders for any protein, such that only those that bind are synthesized. In this Roadmap, we describe the...