Cristian G Bologa
Overview
Explore the profile of Cristian G Bologa including associated specialties, affiliations and a list of published articles.
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64
Citations
3116
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Recent Articles
11.
Jarratt L, Situ J, King R, Montanez Ramos E, Groves H, Ormesher R, et al.
JMIR Med Educ
. 2022 Feb;
8(1):e23845.
PMID: 35142625
Background: On March 11, 2020, the New Mexico Governor declared a public health emergency in response to the COVID-19 pandemic. The New Mexico medical advisory team contacted University of New...
12.
Kropiwnicki E, Binder J, Yang J, Holmes J, Lachmann A, Clarke D, et al.
Curr Protoc
. 2022 Jan;
2(1):e355.
PMID: 35085427
The Illuminating the Druggable Genome (IDG) consortium is a National Institutes of Health (NIH) Common Fund program designed to enhance our knowledge of under-studied proteins, more specifically, proteins unannotated within...
13.
Bologa C, Pankratz V, Unruh M, Roumelioti M, Shah V, Shaffi S, et al.
BMC Med Res Methodol
. 2021 Jul;
21(1):151.
PMID: 34303362
Background: Converting electronic health record (EHR) entries to useful clinical inferences requires one to address the poor scalability of existing implementations of Generalized Linear Mixed Models (GLMM) for repeated measures....
14.
Yang J, Grissa D, Lambert C, Bologa C, Mathias S, Waller A, et al.
Bioinformatics
. 2021 Jun;
37(21):3865-3873.
PMID: 34086846
Motivation: Genome-wide association studies can reveal important genotype-phenotype associations; however, data quality and interpretability issues must be addressed. For drug discovery scientists seeking to prioritize targets based on the available...
15.
Bocci G, Bradfute S, Ye C, Garcia M, Parvathareddy J, Reichard W, et al.
ACS Pharmacol Transl Sci
. 2020 Dec;
3(6):1278-1292.
PMID: 33330842
The urgent need for a cure for early phase COVID-19 infected patients critically underlines drug repositioning strategies able to efficiently identify new and reliable treatments by merging computational, experimental, and...
16.
Sheils T, Mathias S, Kelleher K, Siramshetty V, Nguyen D, Bologa C, et al.
Nucleic Acids Res
. 2020 Nov;
49(D1):D1334-D1346.
PMID: 33156327
In 2014, the National Institutes of Health (NIH) initiated the Illuminating the Druggable Genome (IDG) program to identify and improve our understanding of poorly characterized proteins that can potentially be...
17.
Avram S, Bologa C, Holmes J, Bocci G, Wilson T, Nguyen D, et al.
Nucleic Acids Res
. 2020 Nov;
49(D1):D1160-D1169.
PMID: 33151287
DrugCentral is a public resource (http://drugcentral.org) that serves the scientific community by providing up-to-date drug information, as described in previous papers. The current release includes 109 newly approved (October 2018...
18.
Sheils T, Mathias S, Siramshetty V, Bocci G, Bologa C, Yang J, et al.
Curr Protoc Bioinformatics
. 2020 Jan;
69(1):e92.
PMID: 31898878
Pharos is an integrated web-based informatics platform for the analysis of data aggregated by the Illuminating the Druggable Genome (IDG) Knowledge Management Center, an NIH Common Fund initiative. The current...
19.
Revankar C, Bologa C, Pepermans R, Sharma G, Petrie W, Alcon S, et al.
Cell Chem Biol
. 2019 Nov;
26(12):1692-1702.e5.
PMID: 31706983
Estrogen exerts extensive and diverse effects throughout the body of women. In addition to the classical nuclear estrogen receptors (ERα and ERβ), the G protein-coupled estrogen receptor GPER is an...
20.
Bologa C, Ursu O, Oprea T
Methods Mol Biol
. 2019 Mar;
1939:119-138.
PMID: 30848459
Virtual screening is a well-established technique that has proven to be successful in the identification of novel biologically active molecules, including drug repurposing. Whether for ligand-based or for structure-based virtual...