Claudio Viegas Jr
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Explore the profile of Claudio Viegas Jr including associated specialties, affiliations and a list of published articles.
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35
Citations
404
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Recent Articles
1.
Espino Urena M, Katchborian-Neto A, Garcez Neto J, da Silva Lopes F, de Morais S, Narciso Dos Reis V, et al.
Vet Sci
. 2025 Feb;
12(2).
PMID: 40005850
Gastrointestinal nematode infections significantly impact small ruminant production, causing substantial economic losses worldwide. The rising resistance to anthelmintics has led to the search for alternative treatments, including phytotherapeutic approaches. This...
2.
de Freitas Silva M, Juliet Cristancho Ortiz C, Ferreira Coelho L, Pruccoli L, Pagliarani B, Pisani L, et al.
Bioorg Chem
. 2024 Jun;
150:107587.
PMID: 38941700
Molecular hybridization between structural fragments from the structures of curcumin (1) and resveratrol (2) was used as a designing tool to generate a new N-acyl-cinnamoyl-hydrazone hybrid molecular architecture. Twenty-eight new...
3.
de Souza A, Dias Viegas F, Silva Gontijo V, Vieira Domingues J, Giusti-Paiva A, Vilela F, et al.
Chem Biodivers
. 2023 Dec;
21(3):e202301508.
PMID: 38092696
Dillenia indica (Linn.) has been reported by several biological activities, including anti-inflammatory, antioxidant, antidiabetic, anti-hyperglycemic, antiproliferative, antimutagenic, anticholinesterase, and antimicrobial. In Brazilian traditional medicine, the fruits of D. indica have...
4.
Baptistella M, Assuncao R, Sales de Oliveira C, Siqueira A, Dos Santos E, de Freitas Silva M, et al.
J Pharm Pharmacol
. 2023 Oct;
76(5):479-488.
PMID: 37874746
Objectives: The present study aimed to evaluate the chemopreventive effects of the hybrid against pre-neoplastic lesions induced in the colon of rodents. Methods: The doses were determined based on the...
5.
Pressete C, Dias Viegas F, Campos T, Caixeta E, Hanemann J, Ferreira-Silva G, et al.
Pharmaceuticals (Basel)
. 2023 Jun;
16(2).
PMID: 37259298
Melanoma is considered the most aggressive form of skin cancer, showing high metastatic potential and persistent high mortality rates despite the introduction of immunotherapy and targeted therapies. Thus, it is...
6.
Espino Urena M, Katchborian-Neto A, Trinidad A, Ramirez Ramirez M, Vasquez Tineo M, Vilemar de Araujo-Filho J, et al.
Chem Biodivers
. 2023 May;
20(7):e202300135.
PMID: 37172262
Gastrointestinal nematode parasitism is a major burden to small ruminant production globally, compounded by increasing anthelmintic resistance. Previous studies have identified essential oils (EOs) from the Lippia genus with antiprotozoal...
7.
Macedo Vaz S, de Freitas Silva M, Dos Reis Rosa Franco G, Jorge R Guimaraes M, Motta R da Silva F, Castro N, et al.
Bioorg Med Chem
. 2022 Aug;
71:116952.
PMID: 35930852
The search for new drug candidates against Alzheimer's disease (AD) remains a complex challenge for medicinal chemists due to its multifactorial pathogenesis and incompletely understood physiopathology. In this context, we...
8.
Juliet Cristancho Ortiz C, de Freitas Silva M, Pruccoli L, Nadur N, de Azevedo L, Kummerle A, et al.
RSC Med Chem
. 2022 Jun;
13(5):568-584.
PMID: 35694691
A new series of eight multifunctional thalidomide-donepezil hybrids were synthesized based on the multi-target-directed ligand strategy and evaluated as potential neuroprotective, cholinesterase inhibitors and anti-neuroinflammatory agents against neurodegenerative diseases. A...
9.
Viegas Jr C, Fraga C, Sousa M, Tarozzi A
Front Pharmacol
. 2020 Dec;
11:609274.
PMID: 33362563
No abstract available.
10.
Juliet Cristancho Ortiz C, Damasio C, Pruccoli L, Nadur N, de Azevedo L, Guedes I, et al.
Neurochem Res
. 2020 Oct;
45(12):3003-3020.
PMID: 33079324
A new series of ten multifunctional Cinnamoyl-N-acylhydrazone-donepezil hybrids was synthesized and evaluated as multifunctional ligands against neurodegenerative diseases. The molecular hybridization approach was based on the combination of 1-benzyl-4-piperidine fragment...