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Chun Tu

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Articles 11
Citations 462
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Recent Articles
1.
Hu Z, Wu Z, Luo W, Liu S, Tu C
Sci Total Environ . 2024 Sep; 953:176049. PMID: 39241872
Soil in karst areas commonly exhibits characteristics of heavy metal enrichment. Accurate identification of soil heavy metal distribution, risks, and sources are crucial for preventing soil heavy metal pollution in...
2.
Tu C, Li F
J Environ Sci (China) . 2017 Apr; 54:314-327. PMID: 28391942
Understanding the effects of warming on greenhouse gas (GHG, such as NO, CH and CO) feedbacks to climate change represents the major environmental issue. However, little information is available on...
3.
Huo L, Li C, Huang T, Lam Y, Xia W, Tu C, et al.
Am J Transl Res . 2015 Jan; 6(6):649-63. PMID: 25628777
Nuclear translocation of EGFR has been shown to be important for tumor cell growth, survival, and therapeutic resistance. Previously, we detected the association of EGFR with Keap1 in the nucleus....
4.
Ahmad G, Mohapatra B, Schulte N, Nadeau S, Luan H, Zutshi N, et al.
Int J Biochem Cell Biol . 2014 Dec; 57:123-34. PMID: 25449262
Members of the casitas B-lineage lymphoma (Cbl) family (Cbl, Cbl-b and Cbl-c) of ubiquitin ligases serve as negative regulators of receptor tyrosine kinases (RTKs). An essential role of Cbl-family protein-dependent...
5.
Huang T, Huo L, Wang Y, Xia W, Wei Y, Chang S, et al.
Cancer Cell . 2013 Jun; 23(6):796-810. PMID: 23764002
Epidermal growth factor receptor (EGFR) initiates a signaling cascade that leads to DNA synthesis and cell proliferation, but its role in regulating DNA replication licensing is unclear. Here, we show...
6.
Tu C, Ahmad G, Mohapatra B, Bhattacharyya S, Ortega-Cava C, Chung B, et al.
Bioarchitecture . 2011 Aug; 1(1):45-48. PMID: 21866262
ESCRT pathway proteins play a key role in sorting ubiquitinated membrane receptors towards lysosomes providing an important mechanism for attenuating cell surface receptor signaling. However, recent studies point to a...
7.
Tu C, Ortega-Cava C, Winograd P, Stanton M, Reddi A, Dodge I, et al.
Proc Natl Acad Sci U S A . 2010 Sep; 107(37):16107-12. PMID: 20805499
Active Src localization at focal adhesions (FAs) is essential for cell migration. How this pool is linked mechanistically to the large pool of Src at late endosomes (LEs)/lysosomes (LY) is...
8.
Chung B, Raja S, Clubb R, Tu C, George M, Band V, et al.
BMC Cell Biol . 2009 Dec; 10:84. PMID: 19948031
Background: Epidermal growth factor receptor (EGFR) controls a wide range of cellular processes, and altered EGFR signaling contributes to human cancer. EGFR kinase domain mutants found in non-small cell lung...
9.
Duan L, Chen G, Virmani S, Ying G, Raja S, Chung B, et al.
J Biol Chem . 2009 Oct; 285(2):1555-68. PMID: 19826000
Non-malignant mammary epithelial cells (MECs) undergo acinar morphogenesis in three-dimensional Matrigel culture, a trait that is lost upon oncogenic transformation. Rho GTPases are thought to play important roles in regulating...
10.
Tu C, Ortega-Cava C, Chen G, Fernandes N, Cavallo-Medved D, Sloane B, et al.
Cancer Res . 2008 Nov; 68(22):9147-56. PMID: 19010886
Podosomes mediate cell migration and invasion by coordinating the reorganization of actin cytoskeleton and focal matrix degradation. MMP and serine proteases have been found to function at podosomes. The lysosomal...