Cesar F Ortega-Cava
Overview
Explore the profile of Cesar F Ortega-Cava including associated specialties, affiliations and a list of published articles.
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10
Citations
318
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Recent Articles
1.
Ortega-Cava C, Raja S, Laiq Z, Bailey T, Luan H, Mohapatra B, et al.
J Carcinog
. 2011 Dec;
10:29.
PMID: 22190871
Background: Well over a quarter of human breast cancers are ErbB2-driven and constitute a distinct subtype with substantially poorer prognosis. Yet, there are substantial gaps in our understanding of how...
2.
Tu C, Ahmad G, Mohapatra B, Bhattacharyya S, Ortega-Cava C, Chung B, et al.
Bioarchitecture
. 2011 Aug;
1(1):45-48.
PMID: 21866262
ESCRT pathway proteins play a key role in sorting ubiquitinated membrane receptors towards lysosomes providing an important mechanism for attenuating cell surface receptor signaling. However, recent studies point to a...
3.
Tu C, Ortega-Cava C, Winograd P, Stanton M, Reddi A, Dodge I, et al.
Proc Natl Acad Sci U S A
. 2010 Sep;
107(37):16107-12.
PMID: 20805499
Active Src localization at focal adhesions (FAs) is essential for cell migration. How this pool is linked mechanistically to the large pool of Src at late endosomes (LEs)/lysosomes (LY) is...
4.
Duan L, Chen G, Virmani S, Ying G, Raja S, Chung B, et al.
J Biol Chem
. 2009 Oct;
285(2):1555-68.
PMID: 19826000
Non-malignant mammary epithelial cells (MECs) undergo acinar morphogenesis in three-dimensional Matrigel culture, a trait that is lost upon oncogenic transformation. Rho GTPases are thought to play important roles in regulating...
5.
Tu C, Ortega-Cava C, Chen G, Fernandes N, Cavallo-Medved D, Sloane B, et al.
Cancer Res
. 2008 Nov;
68(22):9147-56.
PMID: 19010886
Podosomes mediate cell migration and invasion by coordinating the reorganization of actin cytoskeleton and focal matrix degradation. MMP and serine proteases have been found to function at podosomes. The lysosomal...
6.
Yuki T, Ishihara S, Rumi M, Ortega-Cava C, Kadowaki Y, Kazumori H, et al.
Am J Physiol Gastrointest Liver Physiol
. 2006 Sep;
291(4):G735-43.
PMID: 16959957
Midkine (MK) is a unique growth and differentiation factor that modulates the proliferation and migration of various cells; however, little is known regarding its relationship to intestinal diseases. The aim...
7.
Ortega-Cava C, Ishihara S, Rumi M, Aziz M, Kazumori H, Yuki T, et al.
Clin Vaccine Immunol
. 2006 Jan;
13(1):132-8.
PMID: 16426010
We recently demonstrated that the pattern recognition receptors (PRRs) toll-like receptor 2 (TLR2), TLR4, and CD14 are expressed in mouse colonic epithelium in a compartmentalized manner. Here we report the...
8.
Kazumori H, Ishihara S, Rumi M, Ortega-Cava C, Kadowaki Y, Kinoshita Y
Am J Physiol Gastrointest Liver Physiol
. 2003 Oct;
286(3):G508-14.
PMID: 14563668
For the production and vesicle storage of histamine, Enterochromaffin-like (ECL) cells express histidine decarboxylase (HDC) and vesicular monoamine transporter 2 (VMAT2). Although HDC and VMAT2 show dynamic changes during gastric...
9.
Ortega-Cava C, Ishihara S, Rumi M, Kawashima K, Ishimura N, Kazumori H, et al.
J Immunol
. 2003 Apr;
170(8):3977-85.
PMID: 12682225
Pattern recognition receptors (PRRs), which include the Toll-like receptors (TLRs), are involved in the innate immune response to infection. TLR4 is a model for the TLR family and is the...
10.
Ortega-Cava C, Ishihara S, Kawashima K, Rumi M, Kazumori H, Adachi K, et al.
Dig Dis Sci
. 2002 Oct;
47(10):2275-85.
PMID: 12395901
Hepatocyte growth factor (HGF), a potent inducer of cell migration with morphogenic and mitogenic actions was reported to have key roles in the repair of various tissues. In order to...