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Tzu-Hsuan Huang

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Articles 38
Citations 1033
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Recent Articles
1.
Ochirbat S, Kan T, Hsu C, Huang T, Chuang K, Chen M, et al.
Angiogenesis . 2024 Aug; 27(4):827-843. PMID: 39177676
Nicotine acts as an angiogenic factor by stimulating endogenous cholinergic pathways. Several subtypes of nicotinic acetylcholine receptors (nAChRs) have been demonstrated to be closely correlated to the formation and progression...
2.
Chiu H, Chou C, Lee K, Shih C, Huang T, Sung L
Int J Biol Macromol . 2024 Apr; 268(Pt 2):131779. PMID: 38679250
Natto contains a potent fibrinolytic enzyme called nattokinase (NK), which has thrombolytic, antihypertensive, antiatherosclerotic and lipid-lowering effects. Although NK has been recognized for its beneficial effect on humans with atherosclerotic...
3.
Begg L, Orriols A, Zannikou M, Yeh C, Vadlamani P, Kanojia D, et al.
Commun Med (Lond) . 2024 Feb; 4(1):22. PMID: 38378783
Background: Understanding why some triple-negative breast cancer (TNBC) patients respond poorly to existing therapies while others respond well remains a challenge. This study aims to understand the potential underlying mechanisms...
4.
Ji C, Kuang B, Buetow B, Vitsky A, Xu Y, Huang T, et al.
PLoS One . 2024 Feb; 19(2):e0298240. PMID: 38315680
PF-07209960 is a novel bispecific fusion protein composed of an anti-PD-1 antibody and engineered IL-15 cytokine mutein with reduced binding affinity to its receptors. The pharmacokinetics (PK), pharmacodynamics (PD), and...
5.
Grassmann F, Malarstig A, Dahl L, Bendes A, Dale M, Thomas C, et al.
Br J Cancer . 2023 Dec; 130(4):620-627. PMID: 38135714
Objective: Current breast cancer risk prediction scores and algorithms can potentially be further improved by including molecular markers. To this end, we studied the association of circulating plasma proteins using...
6.
Malarstig A, Grassmann F, Dahl L, Dimitriou M, McLeod D, Gabrielson M, et al.
Nat Commun . 2023 Nov; 14(1):7680. PMID: 37996402
Biomarkers for early detection of breast cancer may complement population screening approaches to enable earlier and more precise treatment. The blood proteome is an important source for biomarker discovery but...
7.
Begg L, Orriols A, Zannikou M, Yeh C, Vadlamani P, Kanojia D, et al.
bioRxiv . 2023 Oct; PMID: 37790346
It remains elusive why some triple-negative breast cancer (TNBC) patients respond poorly to existing therapies while others respond well. Our retrospective analysis of historical gene expression datasets reveals that increased...
8.
Roger Chen Y, Lee W, Liu B, Yang P, Ho C, Hwang J, et al.
Environ Pollut . 2023 Aug; 336:122405. PMID: 37597736
Air pollution, particularly ambient fine particulate matter (PM) pollution, poses a significant risk to public health, underscoring the importance of comprehending the long-term impact on health burden and expenditure at...
9.
Huang T, Lin Y, Hsiao C, Wang L, Ajibola M, Abdulmajeed W, et al.
Front Cell Neurosci . 2023 Aug; 17:1146278. PMID: 37545878
Inhibitory γ-aminobutyric acid (GABA)-ergic interneurons mediate inhibition in neuronal circuitry and support normal brain function. Consequently, dysregulation of inhibition is implicated in various brain disorders. Parvalbumin (PV) and somatostatin (SST)...
10.
Yeh T, Roger Chen Y, Hsu H, Tsai M, Wu Y, Lo W, et al.
Acta Cardiol Sin . 2023 Jul; 39(4):628-642. PMID: 37456949
Background: Studies on disease burden in Taiwan are lacking. We aimed to quantify the burden of cardiovascular disease (CVD) attributable to high body mass index (BMI) in Taiwan. Methods: Using...