Christopher P Corpe
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Explore the profile of Christopher P Corpe including associated specialties, affiliations and a list of published articles.
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12
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808
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Recent Articles
1.
Pinto A, Hobden M, Brown K, Farrimond J, Targett D, Corpe C, et al.
Food Funct
. 2023 Oct;
14(22):10163-10176.
PMID: 37902089
(Poly)phenol (PP)-rich blackcurrant (BC) extracts reduce postprandial glucose concentrations. Combinations with other fruit (poly)phenols and fruit fibre may enhance the effect. This study investigated the acute effects of combinations of...
2.
OBrien P, Han G, Ganpathy P, Pitre S, Zhang Y, Ryan J, et al.
Int J Mol Sci
. 2020 Dec;
22(1).
PMID: 33375525
The gastrointestinal tract (GIT) plays a key role in regulating nutrient metabolism and appetite responses. This study aimed to identify changes in the GIT that are important in the development...
3.
Prpa E, Corpe C, Atkinson B, Blackstone B, Leftley E, Parekh P, et al.
J Nutr Biochem
. 2020 Aug;
85:108466.
PMID: 32739411
Background: Previous research demonstrated that a high dose of phlorizin-rich apple extract (AE) can markedly inhibit early-phase postprandial glycemia, but efficacy of lower doses of the AE is unclear. Objective:...
4.
Ni D, Ai Z, Munoz-Sandoval D, Suresh R, Ellis P, Yuqiong C, et al.
FASEB J
. 2020 Jun;
34(8):9995-10010.
PMID: 32564472
Tea polyphenolics have been suggested to possess blood glucose lowering properties by inhibiting sugar transporters in the small intestine and improving insulin sensitivity. In this report, we studied the effects...
5.
Castro-Acosta M, Stone S, Mok J, Mhajan R, Fu C, Lenihan-Geels G, et al.
J Nutr Biochem
. 2017 Sep;
49:53-62.
PMID: 28886437
Postprandial glycemic responses to meals are inhibited by polyphenol-rich plant foods. Combinations of polyphenols may be particularly effective through complementary mechanisms. A randomized, controlled, double-blinded cross-over trial was conducted in...
6.
Castro-Acosta M, Lenihan-Geels G, Corpe C, Hall W
Proc Nutr Soc
. 2016 May;
75(3):342-55.
PMID: 27170557
The prevalence of type 2 diabetes (T2D) is predicted to reach unprecedented levels in the next few decades. In addition to excess body weight, there may be other overlapping dietary...
7.
Corpe C, Eck P, Wang J, Al-Hasani H, Levine M
J Biol Chem
. 2013 Feb;
288(13):9092-101.
PMID: 23396969
Intestinal vitamin C (Asc) absorption was believed to be mediated by the Na(+)-dependent ascorbic acid transporter SVCT1. However, Asc transport across the intestines of SVCT1 knock-out mice is normal indicating...
8.
Corpe C, Tu H, Eck P, Wang J, Faulhaber-Walter R, Schnermann J, et al.
J Clin Invest
. 2010 Mar;
120(4):1069-83.
PMID: 20200446
Levels of the necessary nutrient vitamin C (ascorbate) are tightly regulated by intestinal absorption, tissue accumulation, and renal reabsorption and excretion. Ascorbate levels are controlled in part by regulation of...
9.
Kwon O, Eck P, Chen S, Corpe C, Lee J, Kruhlak M, et al.
FASEB J
. 2006 Dec;
21(2):366-77.
PMID: 17172639
We tested whether the dominant intestinal sugar transporter GLUT2 was inhibited by intestinal luminal compounds that are inefficiently absorbed and naturally present in foods. Because of their abundance in fruits...
10.
Chen Q, Espey M, Krishna M, Mitchell J, Corpe C, Buettner G, et al.
Proc Natl Acad Sci U S A
. 2005 Sep;
102(38):13604-9.
PMID: 16157892
Human pharmacokinetics data indicate that i.v. ascorbic acid (ascorbate) in pharmacologic concentrations could have an unanticipated role in cancer treatment. Our goals here were to test whether ascorbate killed cancer...