Christopher Corcoran
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Explore the profile of Christopher Corcoran including associated specialties, affiliations and a list of published articles.
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29
Citations
771
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Recent Articles
1.
Joshi A, Geroldinger A, Jiricka L, Senchaudhuri P, Corcoran C, Heinze G
Stat Methods Med Res
. 2021 Dec;
31(2):253-266.
PMID: 34931909
Poisson regression can be challenging with sparse data, in particular with certain data constellations where maximum likelihood estimates of regression coefficients do not exist. This paper provides a comprehensive evaluation...
2.
Patel D, Mez J, Vardarajan B, Staley L, Chung J, Zhang X, et al.
JAMA Netw Open
. 2019 Mar;
2(3):e191350.
PMID: 30924900
Importance: Some of the unexplained heritability of Alzheimer disease (AD) may be due to rare variants whose effects are not captured in genome-wide association studies because very large samples are...
3.
Ridge P, Karch C, Hsu S, Arano I, Teerlink C, Ebbert M, et al.
Genome Med
. 2018 Jan;
10(1):4.
PMID: 29329552
The original version of this article [1] unfortunately contained a typographical error. The 'Alzheimer's Disease Neuroimaging Initiative' was erroneously included as 'Alzheimer's Disease Neuroimaging Initative' in the author list of...
4.
Ridge P, Karch C, Hsu S, Arano I, Teerlink C, Ebbert M, et al.
Genome Med
. 2017 Nov;
9(1):100.
PMID: 29183403
Background: While age and the APOE ε4 allele are major risk factors for Alzheimer's disease (AD), a small percentage of individuals with these risk factors exhibit AD resilience by living...
5.
Wang G, Fu G, Corcoran C
BMC Genet
. 2015 Dec;
16:148.
PMID: 26698561
Background: Genome-wide association studies (GWAS) interrogate large-scale whole genome to characterize the complex genetic architecture for biomedical traits. When the number of SNPs dramatically increases to half million but the...
6.
Carlsen M, Fu G, Bushman S, Corcoran C
Genetics
. 2015 Dec;
202(2):411-26.
PMID: 26661113
Genome-wide data with millions of single-nucleotide polymorphisms (SNPs) can be highly correlated due to linkage disequilibrium (LD). The ultrahigh dimensionality of big data brings unprecedented challenges to statistical modeling such...
7.
Suyundikov A, Stevens J, Corcoran C, Herrick J, Wolff R, Slattery M
BMC Genomics
. 2015 Dec;
16:1045.
PMID: 26653287
Background: Most currently-used normalization methods for miRNA array data are based on methods developed for mRNA arrays despite fundamental differences between the data characteristics. The application of conventional quantile normalization...
8.
Suyundikov A, Stevens J, Corcoran C, Herrick J, Wolff R, Slattery M
PLoS One
. 2015 Apr;
10(4):e0119876.
PMID: 25849489
Missing data can arise in bioinformatics applications for a variety of reasons, and imputation methods are frequently applied to such data. We are motivated by a colorectal cancer study where...
9.
Wengreen H, Munger R, Cutler A, Quach A, Bowles A, Corcoran C, et al.
Am J Clin Nutr
. 2013 Sep;
98(5):1263-71.
PMID: 24047922
Background: Healthy dietary patterns may protect against age-related cognitive decline, but results of studies have been inconsistent. Objective: We examined associations between Dietary Approaches to Stop Hypertension (DASH)- and Mediterranean-style...
10.
Shih H, Tu C, Cao W, Klein A, Ramsey R, Fennell B, et al.
J Biol Chem
. 2012 Nov;
287(53):44425-34.
PMID: 23148212
Highly specific antibodies to phosphoepitopes are valuable tools to study phosphorylation in disease states, but their discovery is largely empirical, and the molecular mechanisms mediating phosphospecific binding are poorly understood....