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John C S Breitner

Explore the profile of John C S Breitner including associated specialties, affiliations and a list of published articles. Areas
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Articles 117
Citations 4322
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Recent Articles
1.
Yakoub Y, Gonzalez-Ortiz F, Ashton N, Dery C, Strikwerda-Brown C, St-Onge F, et al.
Alzheimers Dement . 2025 Feb; 21(2):e14537. PMID: 40008832
Introduction: We assessed the prognostic accuracy of plasma p-tau217 in predicting the progression to mild cognitive impairment (MCI) in cognitively unimpaired (CU) individuals over a mean follow-up of 5.65 years...
2.
Ao J, Picard C, Auld D, Zetterberg H, Brinkmalm A, Blennow K, et al.
Mol Psychiatry . 2025 Jan; PMID: 39827219
Cognitive dysfunction in Alzheimer's disease (AD) correlates closely with pathology in the neuronal microtubule-associated protein tau. Tau pathology may spread via neural synapses. In a population of cognitively unimpaired elderly...
3.
Yakoub Y, Gonzalez-Ortiz F, Ashton N, Dery C, Strikwerda-Brown C, St-Onge F, et al.
medRxiv . 2024 May; PMID: 38766113
Importance: Positron emission tomography (PET) biomarkers are the gold standard for detection of Alzheimer amyloid and tau . Such imaging can identify cognitively unimpaired (CU) individuals who will subsequently develop...
4.
Baril A, Picard C, Labonte A, Sanchez E, Duclos C, Mohammediyan B, et al.
Sleep . 2024 Mar; 47(6). PMID: 38526098
Study Objectives: Although short sleep could promote neurodegeneration, long sleep may be a marker of ongoing neurodegeneration, potentially as a result of neuroinflammation. The objective was to evaluate sleep patterns...
5.
St-Onge F, Chapleau M, Breitner J, Villeneuve S, Binette A
Brain Commun . 2024 Feb; 6(1):fcae031. PMID: 38410618
The accumulation of tau abnormality in sporadic Alzheimer's disease is believed typically to follow neuropathologically defined Braak staging. Recent PET evidence challenges this belief, however, as accumulation patterns for tau...
6.
Baril A, Picard C, Labonte A, Sanchez E, Duclos C, Mohammediyan B, et al.
Alzheimers Dement (Amst) . 2024 Feb; 16(1):e12521. PMID: 38371359
Introduction: Measuring day-to-day sleep variability might reveal unstable sleep-wake cycles reflecting neurodegenerative processes. We evaluated the association between Alzheimer's disease (AD) fluid biomarkers with day-to-day sleep variability. Methods: In the...
7.
Yakoub Y, Ashton N, Strikwerda-Brown C, Montoliu-Gaya L, Karikari T, Kac P, et al.
Alzheimers Dement . 2023 Jun; 19(12):5620-5631. PMID: 37294682
Introduction: Plasma biomarkers are altered years prior to Alzheimer's disease (AD) clinical onset. Methods: We measured longitudinal changes in plasma amyloid-beta (Aβ) ratio, pTau181, pTau231, neurofilament light chain (NfL), and...
8.
Strikwerda-Brown C, Ozlen H, Binette A, Chapleau M, Marchant N, Breitner J, et al.
Biol Psychiatry Glob Open Sci . 2023 Jan; 3(1):130-138. PMID: 36712573
Background: Mindfulness, defined as nonjudgmental awareness of the present moment, has been associated with an array of mental and physical health benefits. Mindfulness may also represent a protective factor for...
9.
Strikwerda-Brown C, Hobbs D, Gonneaud J, St-Onge F, Binette A, Ozlen H, et al.
JAMA Neurol . 2022 Jul; 79(10):975-985. PMID: 35907254
Importance: National Institute on Aging-Alzheimer's Association (NIA-AA) workgroups have proposed biological research criteria intended to identify individuals with preclinical Alzheimer disease (AD). Objective: To assess the clinical value of these...
10.