Christophe Benoist
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Explore the profile of Christophe Benoist including associated specialties, affiliations and a list of published articles.
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254
Citations
24572
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Recent Articles
1.
Iyer H, Benoist C, Bilbo S, Boulanger L, Burton M, Daniels B, et al.
Nat Immunol
. 2025 Feb;
26(3):325-329.
PMID: 39939753
No abstract available.
2.
Lee J, Yang L, Kotzin J, Ahimovic D, Bale M, Nigrovic P, et al.
J Exp Med
. 2025 Jan;
222(4).
PMID: 39873673
Inflammatory cytokines are fundamental mediators of the organismal response to injury, infection, or other harmful stimuli. To elucidate the early and mostly direct transcriptional signatures of inflammatory cytokines, we profiled...
3.
Marin-Rodero M, Cintado E, Walker A, Jayewickreme T, Pinho-Ribeiro F, Richardson Q, et al.
Sci Immunol
. 2025 Jan;
10(104):eadu2910.
PMID: 39873623
Our understanding of the meningeal immune system has recently burgeoned, particularly regarding how innate and adaptive effector cells are mobilized to meet brain challenges. However, information on how meningeal immunocytes...
4.
Huisman B, Michelson D, Rubin S, Kohlsaat K, Gomarga W, Fang Y, et al.
Immunity
. 2024 Dec;
58(1):108-123.e7.
PMID: 39731911
Thymic mimetic cells are molecular hybrids between medullary-thymic-epithelial cells (mTECs) and diverse peripheral cell types. They are involved in eliminating autoreactive T cells and can perform supplementary functions reflective of...
5.
Wang Y, Zhang Y, Kim K, Han J, Okin D, Jiang Z, et al.
Immunity
. 2024 Nov;
57(12):2737-2754.e12.
PMID: 39571575
Ligand-dependent transcription factors of the nuclear receptor (NR) family regulate diverse aspects of metazoan biology, enabling communications between distant organs via small lipophilic molecules. Here, we examined the impact of...
6.
Chowdhary K, Leon J, Mathis D, Benoist C
Proc Natl Acad Sci U S A
. 2024 Aug;
121(36):e2411301121.
PMID: 39196621
Vertebrate cell identity depends on the combined activity of scores of transcription factors (TF). While TFs have often been studied in isolation, a systematic perspective on their integration has been...
7.
Zhu Y, Meerschaert K, Galvan-Pena S, Bin N, Yang D, Basu H, et al.
Science
. 2024 Aug;
385(6708):eadk1679.
PMID: 39088603
Neuroimmune cross-talk participates in intestinal tissue homeostasis and host defense. However, the matrix of interactions between arrays of molecularly defined neuron subsets and of immunocyte lineages remains unclear. We used...
8.
Jaquish A, Phung E, Gong X, Baldominos-Flores P, Galvan-Pena S, Bursulaya I, et al.
bioRxiv
. 2024 Jul;
PMID: 39026711
Pregnancy brings about profound changes to the mammary gland in preparation for lactation. Changes in immunocyte populations that accompany this rapid remodeling are incompletely understood. We comprehensively analyzed mammary T...
9.
Marin-Rodero M, Reyes E, Walker A, Jayewickreme T, Pinho-Ribeiro F, Richardson Q, et al.
bioRxiv
. 2024 Jul;
PMID: 38948783
One Sentence Summary: A distinct population of regulatory T cells in the murine meninges safeguards homeostasis by keeping local interferon-γ-producing lymphocytes in check, thereby preventing their invasion of the parenchyma,...
10.
Gal-Oz S, Baysoy A, Vijaykumar B, Mostafavi S, Benoist C, Shay T
J Immunol
. 2024 May;
213(1):96-104.
PMID: 38775402
The response to type I IFNs involves the rapid induction of prototypical IFN signature genes (ISGs). It is not known whether the tightly controlled ISG expression observed at the cell...