Cheryl Arrowsmith
Overview
Explore the profile of Cheryl Arrowsmith including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
48
Citations
2108
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Carvalho M, Andrade C, Cabral-Piccin M, Kinker G, Vitiello G, Cambui R, et al.
Cancer Res
. 2025 Feb;
PMID: 39970330
Chimeric antigen receptor (CAR) T cell therapy is increasingly being adopted as a clinical modality for patients with relapsed/refractory hematological malignancies. Despite the clinical efficacy of CAR-T cell therapy, a...
2.
Mettu A, Glavatskikh M, Wang X, Lara Ordonez A, Li F, Chau I, et al.
Chem Sci
. 2025 Jan;
16(8):3430-3439.
PMID: 39877816
Critical Assessment of Computational Hit-Finding Experiments (CACHE) Challenges emerged as real-life stress tests for computational hit-finding strategies. In CACHE Challenge #1, 23 participants contributed their original workflows to identify small-molecule...
3.
Alkhalaf L, Arrowsmith C, Balskus E, Bergamini G, Bhandari R, Chang C, et al.
Nat Chem Biol
. 2024 Dec;
21(1):6-15.
PMID: 39719500
No abstract available.
4.
Wolf E, Herasymenko O, Kutera M, Lento C, Arrowsmith C, Ackloo S, et al.
Anal Chem
. 2024 Jul;
96(32):13015-13024.
PMID: 39074309
Hydrogen-deuterium eXchange mass spectrometry (HDX-MS) is increasingly used in drug development to locate binding sites and to identify allosteric effects in drug/target interactions. However, the potential of this technique to...
5.
Martin H, Hossain M, Wellnitz J, Kelestemur E, Hochuli J, Parveen S, et al.
bioRxiv
. 2024 Jul;
PMID: 39026851
Helicases have emerged as promising targets for the development of antiviral drugs; however, the family remains largely undrugged. To support the focused development of viral helicase inhibitors we identified, collected,...
6.
Eguida M, Bret G, Sindt F, Li F, Chau I, Ackloo S, et al.
J Chem Inf Model
. 2024 Jun;
64(13):5344-5355.
PMID: 38916159
We herewith applied a generic hit identification method (POEM) for difficult targets of known three-dimensional structure, relying on the simple knowledge of physicochemical and topological properties of a user-selected cavity....
7.
Merten E, Sears J, Leisner T, Hardy P, Ghoshal A, Hossain M, et al.
bioRxiv
. 2024 Apr;
PMID: 38562906
Significance Statement: Chikungunya virus is one of the most prominent and widespread alphaviruses and has caused explosive outbreaks of arthritic disease. Currently, there are no FDA-approved drugs to treat disease...
8.
Krishnan R, Lapierre M, Gautreau B, Nixon K, El Ghamrasni S, Patel P, et al.
Nucleic Acids Res
. 2023 Sep;
51(19):10484-10505.
PMID: 37697435
Breast cancer linked with BRCA1/2 mutations commonly recur and resist current therapies, including PARP inhibitors. Given the lack of effective targeted therapies for BRCA1-mutant cancers, we sought to identify novel...
9.
Aakula A, Sharma M, Tabaro F, Natkin R, Kamila J, Honkanen H, et al.
Life Sci Alliance
. 2023 Mar;
6(5).
PMID: 36858798
RAS-mediated human cell transformation requires inhibition of the tumor suppressor protein phosphatase 2A (PP2A). However, the phosphoprotein targets and cellular processes in which RAS and PP2A activities converge in human...
10.
Walton J, Lawson K, Prinos P, Finelli A, Arrowsmith C, Ailles L
Nat Rev Urol
. 2022 Oct;
20(2):96-115.
PMID: 36253570
Biallelic inactivation of the tumour suppressor gene Von Hippel-Lindau (VHL) occurs in the vast majority of clear cell renal cell carcinoma (ccRCC) instances, disrupting cellular oxygen-sensing mechanisms to yield a...